2-羟基-4-三氟甲基苯胺合成路线 （共 4 条）
反应条件
tin(ll) chloride in ethanol 10 h; Reflux;
参考文献
Perez-Bolivar, Cesar; Takizawa, Shin-Ya; Nishimura, Go; Montes, Victor A.; Anzenbacher, Pavel
Chemistry - A European Journal, 2011 , vol. 17, # 33 p. 9076 - 9082
反应条件
2-picoline; Na2S2O5; sulfur dioxide; zinc in N,N-dimethyl-formamide T=65°C; P=2250.2 - 3750.3 Torr; 2 h;
参考文献
Tordeux, Marc; Langlois, Bernard; Wakselman, Claude
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 8 p. 2293 - 2299
反应条件
1: acetic acid; nitric acid / 1 h / 20 - 40 °C 2: acetic acid; iron / water / 0.75 h / 135 °C View Scheme
参考文献
Kozic, Jan; Novotna, Eva; Volkova, Marie; Stolarikova, Jirina; Trejtnar, Frantisek; Wsol, Vladimir; Vinsova, Jarmila
European Journal of Medicinal Chemistry, 2012 , vol. 56, p. 108 - 119
反应条件
1: NaNO2; aqueous H2SO4 / anschliessendes Erhitzen mit wss. CuSO4 2: Raney nickel; ethanol / Hydrogenation View Scheme
参考文献
Belcher et al.
Journal of the Chemical Society, 1954 , p. 3846,3849
