1-(3-三氟甲基苯基)乙醇合成路线 （共 40 条）
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol 16 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Organic and Biomolecular Chemistry, , vol. 7, # 21 p. 4470 - 4474
反应条件
C32H31Cl2N4OPRu; potassium isopropoxide T=30°C; P=750.075 Torr; 0.333333 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemistry - A European Journal, , vol. 18, # 35 p. 10843 - 10846
反应条件
palladium diacetate; oxygen; (-)-sparteine in 1,2-dichloro-ethane T=60°C;
参考文献
Journal of the American Chemical Society, , vol. 123, # 30 p. 7475 - 7476
反应条件
1: With (-)-(R,R)-TADDOL; aluminum isopropoxide in diphenylether T=90°C; 1 h; 2: α-methyl-3-trifluoromethylbenzyl alcohol in diphenylether T=90°C; 0.166667 h; Product distribution / selectivity;
参考文献
US2009/30235 A1, ;
Page/Page column 12 ;
反应条件
[(C4Ph4COHOCC4Ph4)(μ-H)][(CO)4Ru2]; Novozym(R) 435; 2,4-dimethylpentan-3-one in toluene T=70°C; P=142.511 Torr; 40 h;
参考文献
Tetrahedron Asymmetry, , vol. 16, # 9 p. 1603 - 1610
反应条件
1: diisopropyl ether / 4 h / 30 °C / lipase QL 2: LiAlH4 / diethyl ether / 6 h / Heating View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 7, # 11 p. 3285 - 3294
反应条件
M. esculenta enzyme preparation immobilized on alginate gel in diethyl ether T=45°C; 116 h;
参考文献
Tetrahedron Asymmetry, , vol. 19, # 12 p. 1418 - 1423
反应条件
oxygen; acetic acid; [Pd{N,N'-di(2,6-di-iPrC6H3)dihydroimidazol-2-yl}(OAc)2(H2O)] in toluene T=60°C; 12 h;
参考文献
Schultz, Mitchell J.; Hamilton, Steven S.; Jensen, David R.; Sigman, Matthew S.
Journal of Organic Chemistry, 2005 , vol. 70, # 9 p. 3343 - 3352
反应条件
palladium diacetate; oxygen; (-)-sparteine in 1,2-dichloro-ethane T=60°C;
参考文献
Jensen; Pugsley; Sigman
Journal of the American Chemical Society, 2001 , vol. 123, # 30 p. 7475 - 7476
反应条件
[(C4Ph4COHOCC4Ph4)(μ-H)][(CO)4Ru2]; Novozym(R) 435; 2,4-dimethylpentan-3-one in toluene T=70°C; P=142.511 Torr; 40 h;
参考文献
Verzijl, Gerard K.M.; De Vries, Johannes G.; Broxterman, Quirinus B.
Tetrahedron Asymmetry, 2005 , vol. 16, # 9 p. 1603 - 1610
