2,2,5,5-四甲基环戊酮合成路线 （共 23 条）
反应条件
1: 62 percent / a.) 96 h, 130 - 145 deg C, b.) 48 h, 175 deg C
2: 80 percent / HNiPr2, POCl3 / CH2Cl2 / a.) 1h, 0 deg C, b.) 1 h, r. t.
3: 95 percent / 70 °C / 0.2 Torr
4: 75 percent / 100percent H3PO4 / 2 h / 150 - 160 °C
View Scheme
参考文献
Luening, Ulrich; Mueller, Michael; Gelbert, Markus; Ruechardt, Christoph
Chemische Berichte, 1991 , vol. 124, # 11 p. 2555 - 2556
反应条件
1: LiAlH4 / diethyl ether
2: (i) NaH, imidazole, THF, (ii) /BRN= 1098293/, (iii) /BRN= 969135/
3: nBu3SnH / xylene
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参考文献
Beckwith,A.L.J.; Lawrence,T.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1979 , p. 1535 - 1539
反应条件
1: 24 percent / hydroxylamine hydrochloride, 15percent aq. NaOH / aq. ethanol / 120 h / Heating
2: 41 percent / nitrosyl chloride / tetrahydrofuran; pyridine / 2.5 h / -20 °C
3: 80 percent / ammonia / tetrahydrofuran / 4 h / 0 °C
View Scheme
参考文献
Guziec, Frank S.; Russo, Joseph M.
Synthesis, 1984 , # 6 p. 479 - 481
