2-苯基-4-喹啉羧酸甲酯合成路线 （共 21 条）
反应条件
indium(III) chloride in acetonitrile
aza-Diels-Alder reaction; 0.05 h; Heatingmicrowave irradiation; Title compound not separated from byproducts;
参考文献
Duvelleroy, Dorothee; Perrio, Cecile; Parisel, Olivier; Lasne, Marie-Claire
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3794 - 3804
反应条件
1: sulfuric acid / 60 - 90 °C
2: potassium hydroxide / ethanol / 72.5 h / |Reflux
3: thionyl chloride / 4 h / |Reflux
View Scheme
参考文献
Shi, Zhi-Bing; Zhang, Lei; Bin, Zheng-Yang; Cao, Xiang-Rong; Gong, Zhu-Nan; Li, Jian-Xin
Letters in Drug Design and Discovery, 2013 , vol. 10, # 5 p. 420 - 426
反应条件
1: potassium hydroxide / ethanol / 72.5 h / |Reflux
2: thionyl chloride / 4 h / |Reflux
View Scheme
参考文献
Shi, Zhi-Bing; Zhang, Lei; Bin, Zheng-Yang; Cao, Xiang-Rong; Gong, Zhu-Nan; Li, Jian-Xin
Letters in Drug Design and Discovery, 2013 , vol. 10, # 5 p. 420 - 426
反应条件
T=80 - 100°C; im Rohr;
参考文献
Claus; Brandt
Justus Liebigs Annalen der Chemie, 1894 , vol. 282, p. 106
反应条件
in dichloromethane
1 h;
参考文献
Kaneko, Chikara; Fujii, Harue; Kawai, Shinji; Hashiba, Kazuhiko; Karasawa, Yoshio; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 74 - 86
反应条件
1 h; Heating; Yield given;
参考文献
Brown, Roger F. C.; Coulston, Karen J.; Eastwood, Frank W.; Jurss, Craig J.
Australian Journal of Chemistry, 1994 , vol. 47, # 3 p. 566 - 570
参考文献
Chem. Fabr. Schering
Patent: DE275963 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 11, p. 973
反应条件
4 h; Irradiation; Further byproducts given;
参考文献
Kaneko, Chikara; Fujii, Harue; Kawai, Shinji; Hashiba, Kazuhiko; Karasawa, Yoshio; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 74 - 86
反应条件
4 h; Irradiationinvestigation of the photochemical Michael reactions; Product distributionMechanism;
参考文献
Kaneko, Chikara; Fujii, Harue; Kawai, Shinji; Hashiba, Kazuhiko; Karasawa, Yoshio; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 74 - 86
反应条件
methanol; sodium tetrahydroborate
T=0 - 35°C;
参考文献
DasGupta, Shirshendu; Murumkar, Prashant R.; Giridhar, Rajani; Yadav, Mange Ram
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 10 p. 3604 - 3617
