反应条件
1: pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1.5 h / Ambient temperature 2: 1.) t-BuOK / 1.) DMF, RT, 5 min, 2.) a) RT, 20 h, b) 90 deg C, 1 h 3: aq. KOH / ethanol / 1 h / Heating 4: thionyl chloride / 1.) RT, 18 h, 2.) 100 deg C, 30 min 5: diethyl ether / 72 h / Ambient temperature 6: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme
参考文献
Gannett, Peter M.; Nagel, Donald L.; Reilly, Pam J.; Lawson, Terence; Sharpe, Jody; Toth, Bela
Journal of Organic Chemistry, 1988 , vol. 53, # 5 p. 1064 - 1071
