2-氯-5-硝基吡啶合成路线

参考文献

ELI LILLY AND COMPANY; BLEISCH, Thomas, John; COATES, David, Andrew; HUGHES, Norman, Earle; JONES, Scott, Alan; NORMAN, Bryan, Hurst
Patent: WO2013/66640 A1, 2013 ;

4548-45-22-氯-5-硝基吡啶+

134469-07-11H-苯并咪唑-2-硫醇

79134-13-7

参考文献

Bourdais; Dauvillier; Gayral; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 3 p. 233 - 239

4548-45-22-氯-5-硝基吡啶+

15091-69-71H-苯并咪唑-2-硫醇钠

79134-13-7

参考文献

El-Bardan, Ali A.; Hamed, Ezzat A.; Aboul-Ela, Salah L.; Moussa, Adel M.
Journal of the Indian Chemical Society, 1997 , vol. 74, # 7 p. 575 - 578

4548-45-22-氯-5-硝基吡啶+

51-52-56-丙基-2-硫尿嘧啶

79134-19-3

参考文献

Bourdais; Dauvillier; Gayral; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 3 p. 233 - 239

4548-45-22-氯-5-硝基吡啶+

51-52-56-丙基-2-硫尿嘧啶

79932-97-1

参考文献

Dupont, L.; Dideberg, O.; Jamoulle, J. C.; Lapiere, C. L.; Bourdais, J.
Bulletin des Societes Chimiques Belges, 1981 , vol. 90, # 9 p. 905 - 914

4548-45-22-氯-5-硝基吡啶+

1116-98-9氰乙酸叔丁酯

914223-27-12-氰基-2-(5-硝基吡啶-2-基)乙酸叔丁酯

参考文献

ENSEMBLE THERAPEUTICS CORPORATION; ALEXANDER, Sethu L.; BRIGGS, Timothy F.; FAVALORO, Frank G., Jr.; HALE, Stephen P.; SEIGAL, Benjamin A.; SHORTSLEEVES, Kelley C.; SNEDEKER, Cheri; TAYLOR, Michael; TERRETT, Nicholas K.; YAN, Dingxue; NOWAK, Pawel, Wojciech; DENNY, Rajiah Aldrin; CHRUNYK, Boris Andrew; SAHASRABUDHE, Parag Vasant; WITHKA, Jane Marie
Patent: WO2014/66726 A2, 2014 ;
Location in patent: Paragraph 00190 ;

4548-45-22-氯-5-硝基吡啶+

2919-23-5环丁醇

916610-34-9

参考文献

Baumann, Christian Andrew; Gaul, Michael David
Patent: US2006/281700 A1, 2006 ;
Location in patent: Page/Page column 41 ;
US 20060281700 A1

4548-45-22-氯-5-硝基吡啶+

920-66-1六氟异丙醇

917924-00-6

参考文献

MITSUI CHEMICALS, INC.
Patent: WO2006/137376 A1, 2006 ;
Location in patent: Page/Page column 181 ;

4548-45-22-氯-5-硝基吡啶

921592-86-1

参考文献

Gruenenthal GmbH; FRANK, Robert; BAHRENBERG, Gregor; CHRISTOPH, Thomas; LESCH, Bernhard; LEE, Jeewoo
Patent: US2013/29962 A1, 2013 ;

4548-45-22-氯-5-硝基吡啶+

118-92-3邻氨基苯甲酸

92516-53-5

参考文献

Petrow
Journal of the Chemical Society, 1945 , p. 927