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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
4-碘三氟甲苯
合成路线
(共 220 条)
455-13-0
4-碘三氟甲苯
+
4529-04-8
丙基锂
→
反应条件
79756-87-9
反应条件
tetrakis(triphenylphosphine) palladium(0); zinc dibromide in tetrahydrofuran T=60°C; Negishi cross-coupling reaction; 4 h;
参考文献
Zhang, Wei; Kraft, Stefan; Moore, Jeffrey S.
Journal of the American Chemical Society, 2004 , vol. 126, # 1 p. 329 - 335
455-13-0
4-碘三氟甲苯
→
反应条件
90141-51-8
反应条件
caesium carbonate; thiourea in dimethyl sulfoxide T=110°C; 12 h; Inert atmosphere; chemoselective reaction;
参考文献
Kamal, Ahmed; Srinivasulu, Vunnam; Murty; Shankaraiah, Nagula; Nagesh, Narayana; Reddy, T. Srinivasa; Subba Rao
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 11-12 p. 2297 - 2307
455-13-0
4-碘三氟甲苯
→
反应条件
18715-45-2
+
90141-51-8
反应条件
sulfur; copper(l) iodide; sodium acetate in N,N-dimethyl-formamide T=100°C; 40 h; Inert atmosphere;
参考文献
Chen, Hsing-Ying; Peng, Wei-Te; Lee, Ying-Hsien; Chang, Yu-Lun; Chen, Yen-Jen; Lai, Yi-Chun; Jheng, Nai-Yuan; Chen, Hsuan-Ying
Organometallics, 2013 , vol. 32, # 19 p. 5514 - 5522
811-97-2
+
455-13-0
4-碘三氟甲苯
→
反应条件
92917-54-9
反应条件
1: 1,1,1-trifluoro-2-fluoroethane With zinc(II) chloride; lithium diisopropyl amide in tetrahydrofuran T=15 - 20°C; 2: 4-trifluoromethyl-1-iodobenzene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=65°C; 1.5 h;
参考文献
Raghavanpillai, Anilkumar; Burton, Donald J.
Journal of Organic Chemistry, 2004 , vol. 69, # 21 p. 7083 - 7091
455-13-0
4-碘三氟甲苯
+
135273-60-8
→
反应条件
97067-18-0
反应条件
potassium fluoride; palladium diacetate; tris-(o-tolyl)phosphine in N,N-dimethyl-formamide T=120°C;
参考文献
Hatanaka, Yasuo; Goda, Ken-ichi; Okahara, Yoshinori; Hiyama, Tamejiro
Tetrahedron, 1994 , vol. 50, # 28 p. 8301 - 8316
455-13-0
4-碘三氟甲苯
+
5142-75-6
→
反应条件
613-33-2
+
97067-18-0
反应条件
caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
455-13-0
4-碘三氟甲苯
+
5720-05-8
→
反应条件
97067-18-0
反应条件
potassium hydroxide in methanol T=50°C; Suzuki coupling; 0.5 h;
参考文献
Tanaka, Shinya; Kaneko, Tetsuro; Asao, Naoki; Yamamoto, Yoshinori; Chen, Mingwei; Zhang, Wei; Inoue, Akihisa
Chemical Communications, 2011 , vol. 47, # 21 p. 5985 - 5987
455-13-0
4-碘三氟甲苯
+
18412-57-2
→
反应条件
97067-18-0
反应条件
copper(l) iodide; cesium fluoride; N,N-dimethyl-2-(diphenylphosphino)benzeneaniline in N,N-dimethyl-formamide T=120°C; Hiyama Coupling; 24 h; Inert atmosphere;
参考文献
Gurung, Santosh K.; Thapa, Surendra; Vangala, Adarsh S.; Giri, Ramesh
Organic Letters, 2013 , vol. 15, # 20 p. 5378 - 5381
455-13-0
4-碘三氟甲苯
+
380481-66-3
→
反应条件
97067-18-0
反应条件
C39H32OP2*CuCl; sodium t-butanolate in toluene T=80°C; Suzuki-Miyaura Coupling; 15 h; Inert atmosphereGlovebox;
参考文献
Zhou, Yiqing; You, Wei; Smith, Kevin B.; Brown, M. Kevin
Angewandte Chemie - International Edition, 2014 , vol. 53, # 13 p. 3475 - 3479
Angew. Chem., 2014 , vol. 126, # 13 p. 3543 - 3547,5
455-13-0
4-碘三氟甲苯
+
5720-07-0
→
反应条件
10355-12-1
反应条件
sodium carbonate; trisphosphine-based palladium in water T=100°C; Suzuki-Miyaura cross-coupling; 3 h;
参考文献
Yamada, Yoichi M. A.; Maeda, Yasunari; Uozumi, Yasuhiro
Organic Letters, 2006 , vol. 8, # 19 p. 4259 - 4262
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