对氟苯甲砜合成路线

参考文献

Parent, Ephraim E.; Dence, Carmen S.; Jenks, Carl; Sharp, Terry L.; Welch, Michael J.; Katzenellenbogen, John A.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 5 p. 1028 - 1040

455-15-2对氟苯甲砜

453-72-52-氟-5-甲基磺酰硝基苯

参考文献

WO2008/84300 A1, ;

Page/Page column 90 ;
WO 2008/084300 A1

455-15-2对氟苯甲砜

14763-60-14-羟基苯甲砜

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 12 p. 3916 - 3920

455-15-2对氟苯甲砜

752242-45-83-羟基-5-(4-(甲基磺酰基)苯氧基)苯甲酸甲酯

参考文献

Bristol-Myers Squibb Company
Patent: US2008/9465 A1, 2008 ;
Location in patent: Page/Page column 78 ;
US 20080009465 A1

455-15-2对氟苯甲砜+

2150-44-93,5-二羟基苯甲酸甲酯

752242-45-83-羟基-5-(4-(甲基磺酰基)苯氧基)苯甲酸甲酯

参考文献

Bristol-Myers Squibb Company
Patent: US2008/9465 A1, 2008 ;
Location in patent: Page/Page column 51 ;
US 20080009465 A1

参考文献

The Dow Chemical Company
Patent: US4349568 A1, 1982 ;

455-15-2对氟苯甲砜+

54915-31-03-(苄氧基)-5-羟基苯甲酸甲酯

871656-49-43-[4-(甲基磺酰基)苯氧基]-5-(苯基甲氧基)-苯甲酸甲酯

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/121110 A1, 2005 ;
Location in patent: Page/Page column 90 ;
WO 2005/121110 A1

37622-90-54-吡唑甲酸乙酯+

455-15-2对氟苯甲砜

918967-65-4

参考文献

PROSIDION LIMITED
Patent: WO2007/3960 A1, 2007 ;
Location in patent: Page/Page column 31-32 ;
WO 2007/003960 A1

106-44-5+

455-15-2对氟苯甲砜

99902-90-6

参考文献

Markley; Tong; Dulworth; Steward; Goralski; Johnston; Wood; Vinogradoff; Bargar
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 427 - 433

108-43-03-氯苯酚+

455-15-2对氟苯甲砜

99902-91-7

参考文献

Markley; Tong; Dulworth; Steward; Goralski; Johnston; Wood; Vinogradoff; Bargar
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 427 - 433