1-氟-4-(三甲基硅基)苯合成路线 （共 39 条）
反应条件
1: 1-bromo-4-fluorobenzene With tert.-butyl lithium in tetrahydrofuran; pentane T=-75°C; 0.25 h; 2: chloro-trimethyl-silane in tetrahydrofuran; pentane
参考文献
Heiss, Christophe; Marzi, Elena; Mongin, Florence; Schlosser, Manfred
European Journal of Organic Chemistry, 2007 , # 4 p. 669 - 675
参考文献
Gmelin Handbook: Si: MVol.C, 22, page 68 - 71
反应条件
potassium fluoride; tris-(dibenzylideneacetone)dipalladium(0); biphenyl-2-yl-di-tert-butyl-phosphane in various solvent(s) T=100°C; Substitution; silylation;
参考文献
Goossen; Ferwanah
Synlett, 2000 , # 12 p. 1801 - 1803
反应条件
[RhCl(η2:η2-cycloocta-1,5-diene)]2 in various solvent(s) T=130°C; 15 h;
参考文献
Tobisu, Mamoru; Kita, Yusuke; Chatani, Naoto
Journal of the American Chemical Society, 2006 , vol. 128, # 25 p. 8152 - 8153
反应条件
1: With sodium hydroxide in methanol T=23°C; 0.25 h; 2: With silver trifluoromethanesulfonate in methanol T=0°C; 0.5 h; 3: With 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) in hexadeuterioacetone 1 h; Molecular sieve;
参考文献
Brenzovich Jr., William E.; Brazeau, Jean-Francois; Toste, F. Dean
Organic Letters, 2010 , vol. 12, # 21 p. 4728 - 4731
参考文献
Chvalovsky, V.; Bazant, V.
Collection of Czechoslovak Chemical Communications, 1951 , vol. 16, p. 580 - 590
Full Text Show Details
Gmelin Handbook: Si: MVol.C, 22, page 68 - 71
反应条件
sodium methylate in N,N,N',N',N'',N''-hexamethylphosphoric triamide 0.5 h;
参考文献
Postigo; Rossi
Organic letters, 2001 , vol. 3, # 8 p. 1197 - 1200
反应条件
in N,N,N',N',N'',N''-hexamethylphosphoric triamide
参考文献
Postigo, Al; Vaillard, Santiago E.; Rossi, Roberto A.
Journal of Physical Organic Chemistry, 2002 , vol. 15, # 12 p. 889 - 893
反应条件
in benzene-d6 20 h; UV-irradiationInert atmosphere;
参考文献
Fortier, Skye; Zhang, Yongqiang; Sharma, Hemant K.; Pannell, Keith H.
Organometallics, 2010 , vol. 29, # 4 p. 1041 - 1044
反应条件
sodium methylate in N,N,N',N',N'',N''-hexamethylphosphoric triamide Product distributionKinetics; Further Variations:Reaction partners;
参考文献
Postigo; Rossi
Organic letters, 2001 , vol. 3, # 8 p. 1197 - 1200
