1: With Et2O*LiN(SiMe3)2 in diethyl ether Inert atmosphere; 2: With hydrogenchloride in diethyl ether; ethanol; water Inert atmosphere; 3: With sodium hydroxide in water Inert atmosphere;
1: (methoxymethyl)-triphenylphosphonium chloride With phenyllithium in tetrahydrofuran T=0°C; Dehydrochlorination; 0.166667 h; 2: p-(trifluoromethyl)-benzonitrile in tetrahydrofuran T=20°C; Alkylation; 2 h; 3: With water in tetrahydrofuran Hydrolysis;