N-(2-溴-3-氧代螺[3.5]壬-1-烯-1-基)-4-(2,7-萘啶-1-基氨基)-L-苯基丙氨酸合成路线 (共 3 条)
反应条件
lithium hydroxide; water in tetrahydrofuran T=20°C; 2 h;
参考文献
WO2004/7494 A1, ;
Page 18 ;
反应条件
human liver microsomes in aq. phosphate buffer T=37°C; pH=7.4; 0.166667 h; Enzymatic reaction;
参考文献
Drug Metabolism and Disposition, , vol. 42, # 1 p. 153 - 161
反应条件
human liver microsomes in aq. phosphate buffer T=37°C; pH=7.4; 1 h; Enzymatic reaction;
参考文献
Drug Metabolism and Disposition, , vol. 42, # 1 p. 153 - 161