反应条件
1: 1.) aq. 10 percent sodium hydroxide, 2.) conc. hydrochloric acid / 1.) reflux, 20 h, 2.) 0 deg C, pH 6
2: LAH / diethyl ether / 1 h / Ambient temperature
3: triethylamine / tetrahydrofuran / 1.) 0 deg C, 30 min, 2.) room temperature, 30 min
4: lithium bromide / tetrahydrofuran / 4 h / Heating
View Scheme
参考文献
Becker; Haddad
Tetrahedron, 1993 , vol. 49, # 4 p. 947 - 964