反应条件
1: 1.) n-BuLi, 2.) I2 / 1.) THF, hexane, -70 deg C, 10 min, 2.) THF, hexane, -70 deg C, 10 min
2: 39 percent / Mg / tetrahydrofuran / 0.5 h / Heating
View Scheme
参考文献
SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Yingjun; ZHANG, Jiancun; XIE, Hongming; REN, Qingyun; TAN, Yumei; LUO, Huichao
Patent: WO2014/19344 A1, 2014 ;
