1: 1-fluoro-3-methoxybenzene With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-78°C; 1 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane 1 h; 3: With hydrogenchloride; water in tetrahydrofuran; hexane
参考文献
Rhizen Pharmaceuticals SA
Patent: US2012/289496 A1, 2012 ;
Location in patent: Page/Page column 100 ;