1-(3-氨丙基)-4-甲基哌嗪合成路线 （共 13 条）
反应条件
sodium in ethanol Reflux;
参考文献
Synthesis (Germany), , vol. 45, # 1 art. no. SS-2012-H0716-OP, p. 45 - 52
反应条件
1: With hydrazine hydrate in methanol; ethanol 4 h; Reflux; 2: With hydrogenchloride in methanol; ethanol; water 1 h; Reflux;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 17 p. 5264 - 5270
反应条件
1: K2CO3 / dimethylformamide / 4 h / 90 °C 2: N2H2*H2O / ethanol / 3 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 13 p. 2131 - 2135
反应条件
nickel; dimethyl amine; benzene Hydrogenation;
参考文献
Yakugaku Zasshi, , vol. 76, p. 644,647, 648
Chem.Abstr., , p. 425
反应条件
nickel; benzene Hydrogenation;
参考文献
Yakugaku Zasshi, , vol. 76, p. 644,647, 648
Chem.Abstr., , p. 425
参考文献
Hoechst Aktiengesellschaft
Patent: US5232922 A1, 1993 ;
参考文献
Chakrabarti, Jiban K.; Horsman, Linda; Hotten, Terrence M.; Pullar, Ian A.; Tupper, David E.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 878 - 884
反应条件
in ethanol
1.5 h; Heating;
参考文献
Kesten, Stephen J.; Degnan, Margaret J.; Hung, Jocelyn; McNamara, Dennis J.; Ortwine, Daniel F.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 19 p. 3429 - 3447
反应条件
sodium carbonate in ethanol
15 h; Heating; Yield given;
参考文献
Groszkowski; Wesolowska
Archiv der Pharmazie, 1982 , vol. 315, # 2 p. 136 - 142
反应条件
sodium carbonate in ethanol
15 h; Heating; Yield given;
参考文献
Groszkowski; Wesolowska
Archiv der Pharmazie, 1982 , vol. 315, # 2 p. 136 - 142
