4,5-二氢-2-(2-噻吩)-1H-咪唑合成路线 （共 16 条）
反应条件
1: SOCl2 / toluene / 16 h / 20 °C
2: 87 percent / 10 h / Heating
View Scheme
参考文献
Chadwick; Ennis
Tetrahedron, 1991 , vol. 47, # 47 p. 9901 - 9914
反应条件
1: 2-methyl-propan-2-ol / 20 °C
2: tert-butyl hypochlorite / 2-methyl-propan-2-ol / 10 h / 50 °C
View Scheme
参考文献
Ishihara, Midori; Togo, Hideo
Synthesis, 2007 , # 13 p. 1939 - 1942
参考文献
Chadwick; Ennis
Tetrahedron, 1991 , vol. 47, # 47 p. 9901 - 9914
反应条件
in tetrahydrofuran
Heating;
参考文献
George,B.; Papadopoulos,E.P.
Journal of Organic Chemistry, 1977 , vol. 42, p. 441 - 443
反应条件
trimethylaluminum
Yield given. Multistep reaction;
参考文献
Neef, Guenter; Eder, Ulrich; Sauer, Gerhard
Journal of Organic Chemistry, 1981 , vol. 46, # 13 p. 2824 - 2826
反应条件
1: 96 percent / 24 h / 20 °C
2: 87 percent / acetonitrile / 10 h / Heating
View Scheme
参考文献
Chadwick; Ennis
Tetrahedron, 1991 , vol. 47, # 47 p. 9901 - 9914
