4-氨基-5-氯-2-甲氧基-3-硝基-苯甲酸甲酯合成路线 （共 3 条）
反应条件
1: With sulfuric acid in methanol
7 h; Reflux;
2: With sodium hydrogencarbonate in water
参考文献
InterMune, Inc.
Patent: US2011/152246 A1, 2011 ;
Location in patent: Page/Page column 193 ;
反应条件
1: 91 percent / HNO3 / 0.17 h / 20 °C
2: 94 percent / aq. H2SO4 / methanol / 9 h / Heating
View Scheme
参考文献
Renneberg, Dorte; Dervan, Peter B.
Journal of the American Chemical Society, 2003 , vol. 125, # 19 p. 5707 - 5716
反应条件
hydrogen; triethylamine; palladium on activated charcoal
P=3800 Torr; 6 h;
参考文献
California Institute of Technology
Patent: US2005/26174 A1, 2005 ;
