1: 3-chloro-pyridine With n-butyllithium; diisopropylamine in diethyl ether T=-60°C; 0.75 h; 2: With tri-isopropoxy-borane in diethyl ether T=-60 - 10°C; 3: 2,3-dimethylbutane-2,3-diol With acetic acid in diethyl ether 4 h;

1: lithium diisopropylamide / tetrahydrofuran; hexane / 2 h / -78 °C 2: hexane; tetrahydrofuran / -78 - 20 °C View Scheme

in tetrahydrofuran; hexane T=-78 - 20°C;