Merck and Co., Inc.
Patent: US5719147 A1, 1998 ;
US 5719147 A
Title/Abstract Full Text Show Details
Merck and Co., Inc.
Patent: US5637699 A1, 1997 ;
US 5637699 A
1: N-methyl-N-nitrosourea With potassium hydroxide in diethyl ether; water
2: 4-fluorophenylacetic acid chloride in diethyl ether
T=0 - 20°C; 0.5 h;
3: With hydrogen bromide in diethyl ether; water
T=-30 - 20°C; 1 h;
参考文献
SHIONOGI and CO., LTD.
Patent: EP1422218 A1, 2004 ;
Location in patent: Page 124 ;