对氟苯乙腈合成路线

452056-80-31-(2-氨基吡啶-4-基)-2-(4-氟苯基)-乙酮

参考文献

Laufer, Stefan A.; Zimmermann, Werner; Ruff, Kathrin J.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6311 - 6325

459-22-3对氟苯乙腈

474709-83-61-(4-氟苯基)-环丙胺

参考文献

Eisai Co., Ltd.
Patent: EP1382603 A1, 2004 ;
Location in patent: Page 160 ;

459-22-3对氟苯乙腈

476472-56-72-(4-氟苯基)-1-(6-甲基-2-吡啶基)乙酮

参考文献

Sawyer, J. Scott; Beight, Douglas W.; Britt, Karen S.; Anderson, Bryan D.; Campbell, Robert M.; Goodson Jr., Theodore; Herron, David K.; Li, Hong-Yu; McMillen, William T.; Mort, Nicholas; Parsons, Stephen; Smith, Edward C. R.; Wagner, Jill R.; Yan, Lei; Zhang, Faming; Yingling, Jonathan M.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 13 p. 3581 - 3584

459-22-3对氟苯乙腈

500370-52-5

参考文献

SHIONOGI and CO., LTD.
Patent: EP1422218 A1, 2004 ;
Location in patent: Page 190; 191 ;

109-04-6邻溴吡啶+

459-22-3对氟苯乙腈

5005-42-5

参考文献

Herold, Franciszek; Kleps, Jerzy; Anulewicz-Ostrowska, Romana; Szczesna, Beata
Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 4 p. 773 - 782

109-09-12-氯吡啶+

459-22-3对氟苯乙腈

5005-42-5

参考文献

Buschauer, Armin
Archiv der Pharmazie (Weinheim, Germany), 1989 , vol. 322, p. 165 - 171

459-22-3对氟苯乙腈+

100-52-7苯甲醛

54648-47-4(2Z)-2-(4-氟苯基)-3-苯基丙烯腈

参考文献

Alberghina, Gaetano; Amato, Maria Emanuela; Corsaro, Antonio; Fisichella, Salvatore; Scarlata, Giuseppe
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1985 , p. 353 - 356

56326-92-2

参考文献

The Upjohn Company
Patent: US4065573 A1, 1977 ;

459-22-3对氟苯乙腈+

292638-85-8丙烯酸甲酯

56326-92-2

参考文献

Su, Dai-Shi; Lim, John L.; Markowitz, M. Kristine; Wan, Bang-Lin; Murphy, Kathy L.; Reiss, Duane R.; Harrell, C. Meacham; O'Malley, Stacy S.; Ransom, Rick W.; Chang, Raymond S.L.; Pettibone, Douglas J.; Tang, Cuyue; Prueksaritanont, Thomayant; Freidinger, Roger M.; Bock, Mark G.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 11 p. 3006 - 3009

459-22-3对氟苯乙腈+

298-12-4乙醛酸

58755-90-1

参考文献

Fox, Brian M.; Iio, Kiyosei; Li, Kexue; Choi, Rebeka; Inaba, Takashi; Jackson, Simon; Sagawa, Shoichi; Shan, Bei; Tanaka, Masahiro; Yoshida, Atsuhito; Kayser, Frank
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 20 p. 6030 - 6033