3,5-吡啶二甲酸二乙酯合成路线 （共 24 条）
反应条件
hydrogenchloride; sodium ethanolate
1.) 80 deg C, 10 h, 2.) reflux, 4 h; Yield given. Multistep reaction;
参考文献
El-Hamid Attia; Abo-Ghalia; Abd El-Salam
Pharmazie, 1995 , vol. 50, # 7 p. 455 - 459
参考文献
MERCK FROSST CANADA LTD.
Patent: WO2008/141455 A1, 2008 ;
Location in patent: Page/Page column 49 ;
反应条件
hydrogenchloride in ethanol
参考文献
University of Florida
Patent: US4540564 A1, 1985 ;
Title/Abstract Full Text Show Details
University of Florida
Patent: US4824850 A1, 1989 ;
反应条件
1: ethanolic KOH
2: SOCl2
3: benzene; aqueous NH3
4: POCl3; pyridine
View Scheme
参考文献
Bohlmann et al.
Justus Liebigs Annalen der Chemie, 1954 , vol. 587, p. 162,167
Chemische Berichte, 1956 , vol. 89, p. 792,796
