(+/-)-3-苯基丁酸合成路线 (共 94 条)
参考文献
Jochens, Helge; Bornscheuer, Uwe T.
ChemBioChem, 2010 , vol. 11, # 13 p. 1861 - 1866
反应条件
copper(l) chloride in tetrahydrofuran T=0°C; 0.25 h;
参考文献
Kawashima, Masatoshi; Sato, Toshio; Fujisawa, Tamotsu
Tetrahedron, 1989 , vol. 45, # 2 p. 403 - 412
反应条件
hydrogenchloride 4 h; Heating;
参考文献
Chen, Ying-Chun; Xue, Dong; Deng, Jin-Gen; Cui, Xin; Zhu, Jin; Jiang, Yao-Zhong
Tetrahedron Letters, 2004 , vol. 45, # 7 p. 1555 - 1558
反应条件
1: 81 percent / CuI / diethyl ether / 2.5 h / -20 °C 2: 63 percent / NaOH / methanol; H2O / Ambient temperature View Scheme
参考文献
Nagashima, Hideo; Ozaki, Nobuyasu; Washiyama, Masayoshi; Itoh, Kenji
Tetrahedron Letters, 1985 , vol. 26, # 5 p. 657 - 660
反应条件
aluminium trichloride
参考文献
Gorecha; Pyzuk; Mieczkowski
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 1994 , vol. 249, p. 33 - 42
反应条件
aluminium trichloride; benzene
参考文献
Koelsch; Hochmann; Le Claire
Journal of the American Chemical Society, 1943 , vol. 65, p. 59
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Barltrop et al.
Journal of the Chemical Society, 1956 , p. 2928,2936
反应条件
(S)-1-(diphenylphosphinomethyl)-2-methyl-propylamine; nickel dichloride in diethyl ether T=0°C;
参考文献
Hayashi, Tamio; Kanehira, Koichi; Hioki, Tsuyoshi; Kumada, Makoto
Tetrahedron Letters, 1981 , vol. 22, p. 137 - 140
反应条件
1: With biphenyl; 3-phenyl-l-menthopyrazole; copper(l) chloride in tetrahydrofuran T=-28°C; 1 h; 2: With sodium hydroxide in methanol; diethyl ether 1 h; Heating;
参考文献
Kashima, Choji; Yokoyama, Hiroyo; Shibata, Saori; Fujisawa, Kiyoshi; Nishio, Takehiko
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 4 p. 717 - 719
参考文献
Wotiz et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 6342
反应条件
ethanol; nickel T=40 - 50°C; Hydrogenation;
参考文献
Kuhn; Livada
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1933 , vol. 220, p. 235,242