5-甲基-6(5H)-菲啶酮合成路线 （共 78 条）
反应条件
dichloro bis(acetonitrile) palladium(II); cupric trifluoroacetate; trifluoroacetic acid in 1,4-dioxane
T=110°C;
参考文献
Liang, Dongdong; Hu, Ziwei; Peng, Jiangling; Huang, Jinbo; Zhu, Qiang
Chemical Communications, 2013 , vol. 49, # 2 p. 173 - 175
反应条件
tributylphosphine; 1,3-bis-(diphenylphosphino)propane; N-ethyl-N,N-diisopropylamine; palladium diacetate in N,N-dimethyl-formamide
0.75 h; Heating;
参考文献
Harayama, Takashi; Toko, Hiroko; Kubota, Kyoko; Nishioka, Hiromi; Abe, Hitoshi; Takeuchi, Yasuo
Heterocycles, 2002 , vol. 58, p. 175 - 181
反应条件
palladium diacetate; potassium carbonate; triphenylphosphine in 1-methyl-pyrrolidin-2-one
T=120°C; 24 h; Inert atmosphere;
参考文献
Shen, Zengming; Ni, Zhenjie; Mo, Song; Wang, Jing; Zhu, Yamin
Chemistry - A European Journal, 2012 , vol. 18, # 16 p. 4859 - 4865
反应条件
BaMnO4 in dichloromethane
T=45°C; 12 h; Inert atmosphere;
参考文献
Roman, Daniela Sustac; Takahashi, Yoko; Charette, Andre B.
Organic Letters, 2011 , vol. 13, # 12 p. 3242 - 3245
反应条件
2,2'-azo-bisisobutyronitrile; potassium tert-butylate in benzene
T=110°C; 6 h;
参考文献
Bhakuni, Bhagat Singh; Kumar, Amit; Balkrishna, Shah Jaimin; Sheikh, Javeed Ahmed; Konar, Sanjit; Kumar, Sangit
Organic Letters, 2012 , vol. 14, # 11 p. 2838 - 2841
反应条件
1: 94 percent / NEt3 / CH2Cl2 / 0.5 h / -15 °C
2: 93 percent / Pd(OAc)2; DPPP; Ag2CO3 / dimethylformamide / 5 h / Heating
View Scheme
参考文献
Harayama, Takashi; Akiyama, Toshihiko; Nakano, Yuichiro; Nishioka, Hiromi; Abe, Hitoshi; Takeuchi, Yasuo
Chemical and Pharmaceutical Bulletin, 2002 , vol. 50, # 4 p. 519 - 522
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene
参考文献
Motherwell, William B.; Pennell, Andrew M. K.
Journal of the Chemical Society, Chemical Communications, 1991 , # 13 p. 877 - 879
反应条件
palladium diacetate; tris-(o-tolyl)phosphine; silver carbonate in N,N-dimethyl-formamide
2 h; Heating;
参考文献
Harayama, Takashi; Toko, Hiroko; Kubota, Kyoko; Nishioka, Hiromi; Abe, Hitoshi; Takeuchi, Yasuo
Heterocycles, 2002 , vol. 58, p. 175 - 181
反应条件
in o-xylene
T=180°C; Diels-Alder reaction; 120 h;
参考文献
Fujita, Reiko; Yoshisuji, Toshiteru; Wakayanagi, Sota; Wakamatsu, Hideaki; Matsuzaki, Hisao
Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 2 p. 204 - 208
反应条件
1: 68 percent / 10percent aq. NaOH / 2 h
2: 1.) sodium hydride / 1.) DMSO, 1 h, 2.) 20 min.
3: 45 percent / Bu3SnH, AIBN / 24 h / Heating
View Scheme
参考文献
Bowman, W. Russell; Heaney, Harry; Jordan, Benjamin M.
Tetrahedron, 1991 , vol. 47, # 48 p. 10119 - 10128
