5-甲基-6(5H)-菲啶酮合成路线 （共 78 条）
反应条件
1.1: sodium hydroxide / methanol; water / 3 h / 80 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: palladium diacetate; potassium carbonate; triphenylphosphine / 1-methyl-pyrrolidin-2-one / 24 h / 120 °C / Inert atmosphere
View Scheme
参考文献
Shen, Zengming; Ni, Zhenjie; Mo, Song; Wang, Jing; Zhu, Yamin
Chemistry - A European Journal, 2012 , vol. 18, # 16 p. 4859 - 4865
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere
1.2: 6 h / 20 °C / Inert atmosphere
2.1: sodium hydroxide / methanol; water / 3 h / 80 °C / Inert atmosphere
2.2: Inert atmosphere
3.1: palladium diacetate; potassium carbonate; triphenylphosphine / 1-methyl-pyrrolidin-2-one / 24 h / 120 °C / Inert atmosphere
View Scheme
参考文献
Shen, Zengming; Ni, Zhenjie; Mo, Song; Wang, Jing; Zhu, Yamin
Chemistry - A European Journal, 2012 , vol. 18, # 16 p. 4859 - 4865
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in dichloromethane
1.5 h; Ambient temperaturevar. alkyl bromides, reaction of 6(5H)-phenanthridinethione, other reagent, solvent and time; Product distribution;
参考文献
Majumdar; Chattopadhyay; Gupta
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 12 p. 1138 - 1140
反应条件
potassium hexacyanoferrate(III) in water; acetonitrile
T=25°C; Rate constant;
参考文献
Bunting, John W.; Stefanidis, Dimitrios
Journal of Organic Chemistry, 1986 , vol. 51, # 11 p. 2068 - 2071
反应条件
1: 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide / dichloromethane / Cooling with ice
2: tetrabutylammomium bromide; potassium acetate; palladium diacetate / N,N-dimethyl acetamide; water / 6 h / 90 °C / Sonication
View Scheme
参考文献
Zhang, Lei; Geng, Mei; Teng, Peng; Zhao, Dan; Lu, Xi; Li, Jian-Xin
Ultrasonics Sonochemistry, 2012 , vol. 19, # 2 p. 250 - 256
反应条件
in acetic acid
Ambient temperatureIrradiation;
参考文献
Ninomiya, Ichiya; Kiguchi, Toshiko; Yamauchi, Sadami; Naito, Takeaki
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 197 - 202
反应条件
3,3-dimethylbut-1-ene in benzene
2.5 h; Ambient temperatureIrradiation;
参考文献
Glover, Stephen A.; Goosen, Andre; McCleland, Cedric W.; Schoonraad, Johan L.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1986 , p. 645 - 654
反应条件
1: 68 percent / 10percent aq. NaOH / 2 h
2: 1.) sodium hydride / 1.) DMSO, 1 h, 2.) 20 min.
3: 45 percent / Bu3SnH, AIBN / 24 h / Heating
View Scheme
参考文献
Bowman, W. Russell; Heaney, Harry; Jordan, Benjamin M.
Tetrahedron, 1991 , vol. 47, # 48 p. 10119 - 10128
反应条件
1: 1.) sodium hydride / 1.) DMSO, 1 h, 2.) 20 min.
2: 45 percent / Bu3SnH, AIBN / 24 h / Heating
View Scheme
参考文献
Bowman, W. Russell; Heaney, Harry; Jordan, Benjamin M.
Tetrahedron, 1991 , vol. 47, # 48 p. 10119 - 10128
反应条件
1: methanol / 6 h / Heating
2: 600 °C / 0.01 Torr
View Scheme
参考文献
Lister, Troy; Prager, Rolf H.; Tsaconas, Michael; Wilkinson, Kerry L.
Australian Journal of Chemistry, 2003 , vol. 56, # 9 p. 913 - 916
