2-乙烯基噁唑-4-羧酸乙酯合成路线 （共 4 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane
T=100°C; Stille coupling reaction; 4 h;
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2002 , vol. 4, # 17 p. 2905 - 2907
反应条件
1: With sodium hydrogencarbonate in tetrahydrofuran
T=55 - 60°C; 23 h;
2: With trifluoroacetic anhydride in tetrahydrofuran
T=0 - 20°C;
参考文献
Ahmed, Fahim; Donaldson, William A.
Synthetic Communications, 2003 , vol. 33, # 15 p. 2685 - 2693
反应条件
1: 100 °C
2: 83 percent / t-BuONO; CuCl2 / acetonitrile / 2 h / 80 °C
3: 84 percent / Pd(Ph3P)2Cl2 / dioxane / 4 h / 100 °C
View Scheme
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2002 , vol. 4, # 17 p. 2905 - 2907
反应条件
1: 83 percent / t-BuONO; CuCl2 / acetonitrile / 2 h / 80 °C
2: 84 percent / Pd(Ph3P)2Cl2 / dioxane / 4 h / 100 °C
View Scheme
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2002 , vol. 4, # 17 p. 2905 - 2907
