反应条件
1: With n-butyllithium; tetramethylpiperidine in tetrahydrofuran; hexane
T=-78 - 0°C; 0.333333 h;
2: 3,6-dimethoxy-pyridazines in tetrahydrofuran; hexane
T=-78°C; 0.75 h;
3: With hydrochloric ether; ammonium chloride
more than 3 stages;
参考文献
Beaulieu, Francis; Marinier, Anne; Ouellet, Carl; Roy, Stephan; Wittman, Mark D.
Patent: US2005/54655 A1, 2005 ;
Location in patent: Page/Page column 18-19 ;
US 20050054655 A1
