1-甲基-1H-苯并咪唑-2,5-二胺合成路线 (共 3 条)
反应条件
1: in methanol T=100°C; 2: With polyphosphoric acid T=120°C; 0.5 h;
参考文献
Bella, Maros; Milata, Viktor; Larina, Lyudmila I.
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 2 p. 293 - 296
反应条件
hydrazine; palladium 10 on activated carbon in ethanol
T=80°C; Product distribution / selectivity;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2003/74515 A1, 2003 ;
Location in patent: Page/Page column 109; 106-107; 60 ;
WO 03/074515 A1
反应条件
1: methanol / Reflux
2: hydrogen / methanol / 20 °C / 1500.15 Torr
View Scheme
参考文献
Bella, Maros; Milata, Viktor; Larina, Lyudmila I.
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 2 p. 293 - 296