N-BOC-4-乙氧基哌啶合成路线 (共 2 条)
反应条件
1: With trifluoroacetic acid in dichloromethane 2 h; 2: With potassium carbonate in dichloromethane; water
参考文献
ASTRAZENECA AB
Patent: WO2007/53094 A1, 2007 ;
Location in patent: Page/Page column 79-80 ;
WO 2007/053094 A1
反应条件
1: 1-(tert-Butyloxycarbonyl)-4-piperidinol With sodium hydride in N,N-dimethyl-formamide
T=0°C; 0.25 h;
2: ethyl iodide in N,N-dimethyl-formamide
T=20°C; 18 h;
参考文献
ASTRAZENECA AB
Patent: WO2007/53094 A1, 2007 ;
Location in patent: Page/Page column 79 ;
WO 2007/053094 A1