(2R)-乙基吡咯烷盐酸盐合成路线 （共 2 条）
反应条件
hydrogenchloride; water in 1,4-dioxane
T=90°C; 5 h; Sealed tube;
参考文献
GLAXOSMITHKLINE LLC; AXTEN, Jeffrey, Michael; BRADY, Gerald, Patrick, Jr.; GALLAGHER, Timothy, Francis; HEERDING, Dirk, A.; MEDINA, Jesus, Raul; ROMERIL, Stuart, Paul
Patent: WO2010/120854 A1, 2010 ;
Location in patent: Page/Page column 55 ;
WO 2010/120854 A1
反应条件
hydrogenchloride in 1,4-dioxane
T=20°C; 72 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/19833 A1, 2006 ;
Location in patent: Page/Page column 52 ;
WO 2006/019833 A1
