(S)-A-(氨甲基)-4-甲氧基-苯甲醇合成路线 （共 15 条）
反应条件
1: pyridine / 10 h / Ambient temperature 2: 88 percent / NaBH4 / ethanol / 6 h / 0 °C 3: 4 Angstroem sieves / hexane; tetrahydrofuran / 84 h / 25 °C / lipse from Pseudomonas cepacia 4: 10percent aq. HCl / methanol View Scheme
参考文献
Izumi, Taeko; Fukaya, Katsumi
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 4 p. 1216 - 1221
反应条件
1: 4 Angstroem sieves / hexane; tetrahydrofuran / 84 h / 25 °C / lipse from Pseudomonas cepacia 2: 10percent aq. HCl / methanol View Scheme
参考文献
Izumi, Taeko; Fukaya, Katsumi
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 4 p. 1216 - 1221
反应条件
1: sodium azide; potassium iodide / water; acetonitrile / 1 h / 60 °C / |Green chemistry 2: magnesium sulfate; alcohol dehydrogenase KRED-NADH-110 / isopropyl alcohol; aq. phosphate buffer / 20 h / 30 °C / pH 7 / |Autoclave; |Green chemistry; |Enzymatic reaction 3: hydrogen; sodium hydroxide / water; aq. phosphate buffer / 4 h / 30 °C / 7500.75 Torr / pH 9 / |Green chemistry View Scheme
参考文献
Schrittwieser, Joerg H.; Coccia, Francesca; Kara, Selin; Grischek, Barbara; Kroutil, Wolfgang; D'Alessandro, Nicola; Hollmann, Frank
Green Chemistry, 2013 , vol. 15, # 12 p. 3318 - 3331
反应条件
1.1: silver(l) oxide / dichloromethane / 0 - 20 °C 2.1: C10H18BNO; dimethylsulfide borane complex / tetrahydrofuran / 0 °C / Reflux 2.2: 5 h / 20 °C View Scheme
参考文献
Bosiak, Mariusz J.; Pakulski, Marcin M.
Synthesis, 2011 , # 2 art. no. P14610SS, p. 316 - 324
反应条件
1.1: sodium ethanolate / ethanol / 20 °C 1.2: 24 h / 0 °C 2.1: silver(l) oxide / dichloromethane / 0 - 20 °C 3.1: C10H18BNO; dimethylsulfide borane complex / tetrahydrofuran / 0 °C / Reflux 3.2: 5 h / 20 °C View Scheme
参考文献
Bosiak, Mariusz J.; Pakulski, Marcin M.
Synthesis, 2011 , # 2 art. no. P14610SS, p. 316 - 324
