1: With n-butyllithium in hexane T=-78°C; Metallation; 0.5 h; 2: With tri-isopropoxy-borane in hexane Substitution; 3: 1-bromo-3,5-difluoro-benzene With hydrogenchloride in water Hydrolysis;
参考文献
Zhao, Dalian; Feng, Xu; Chen, Cheng-yi; Tillyer, Rich D.; Grabowski, Edward J. J.; Reider, Paul J.; Black, Cameron; Quimet, Nathalie; Prasit, Peppi
Tetrahedron, 1999 , vol. 55, # 19 p. 6001 - 6018