N-(4-氯苄基)-2-甲基-2-丙胺合成路线 （共 7 条）
反应条件
1.1: triethylamine / dichloromethane / 0 - 20 °C 1.2: 0.25 h / 20 °C 2.1: didodecanoyl peroxide / 1,2-dichloro-ethane / 4 h / Reflux 3.1: trifluorormethanesulfonic acid / 3 h / Reflux View Scheme
参考文献
Lopez-Valdez, German; Olguin-Uribe, Simon; Millan-Ortiz, Alejandra; Gamez-Montano, Rocio; Miranda, Luis D.
Tetrahedron, 2011 , vol. 67, # 14 p. 2693 - 2701
反应条件
N-bromosuccinmide; triphenylphosphine in tetrahydrofuran
T=80°C; 1 h;
参考文献
Cheung, Wai-Hung; Zheng, Shi-Long; Yu, Wing-Yiu; Zhou, Guo-Chuan; Che, Chi-Ming
Organic Letters, 2003 , vol. 5, # 14 p. 2535 - 2538
反应条件
sodium tetrahydroborate in methanol
Heating;
参考文献
Markowicz, Teresa; Skolimowski, Janusz; Skowronski, Romuald
Polish Journal of Chemistry, 1981 , vol. 55, # 12 p. 2505 - 2508
反应条件
triethylamine in dichloromethane
参考文献
Yuan, Hao; Yoo, Woo-Jin; Miyamura, Hiroyuki; Kobayashi, Shu
Journal of the American Chemical Society, 2012 , vol. 134, # 34 p. 13970 - 13973
反应条件
1: lithium perchlorate; TMSCl / diethyl ether / 0.33 h / 20 °C
2: BH3*Et3N; lithium perchlorate / diethyl ether / 1 h / 20 °C
View Scheme
参考文献
Heydari, Akbar; Tavakol, Hossein; Aslanzadeh, Saied; Azarnia, Jamshid; Ahmadi, Nafiseh
Synthesis, 2005 , # 4 art. no. Z17804SS, p. 627 - 633
反应条件
1:
2: With sodium tetrahydroborate in methanol
参考文献
To, Wai-Pong; Tong, Glenna So-Ming; Lu, Wei; Ma, Chensheng; Liu, Jia; Chow, Andy Lok-Fung; Che, Chi-Ming
Angewandte Chemie - International Edition, 2012 , vol. 51, # 11 p. 2654 - 2657
反应条件
in 1,4-dioxane
6 h; Yield given;
参考文献
Glushkov, R. G.; Mashkovskii, M. D.; Suvorov, N. N.; Koslovskii, A. G.; Vinograd, L. Kh.; et al.
Pharmaceutical Chemistry Journal, 1993 , vol. 27, # 8 p. 540 - 545
Khimiko-Farmatsevticheskii Zhurnal, 1993 , vol. 27, # 8 p. 8 - 12
