(R)-(-)-苯基丁二酸合成路线 (共 3 条)
反应条件
sodium hydroxide in methanol; water 1 h; Heating;
参考文献
Auburn, Pamela R.; Mackenzie, Peter B.; Bosnich, B.
Journal of the American Chemical Society, 1985 , vol. 107, # 7 p. 2033 - 2046
参考文献
Krause, Hanswalter; Sailer, Cornelia
Journal of Organometallic Chemistry, 1992 , vol. 423, # 2 p. 271 - 279
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Shiraiwa, Tadashi; Sado, Yujin; Fujii, Shigeru; Nakamura, Mitsuhiro; Kurokawa, Hidemoto
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 2 p. 824 - 826
反应条件
sodium hydroxide; thionyl chloride; (-)-Brucine multistep reaction; 2.) 100 deg C; the ratio of the racemization; Product distribution;
参考文献
Brunner, H.; Zettlmeier, W.
Bulletin des Societes Chimiques Belges, 1991 , vol. 100, # 3 p. 259 - 265