6-甲基-5-庚烯-2-醇合成路线 （共 96 条）
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=20°C; 72 h;
参考文献
Martin-Matute, Belen; Edin, Michaela; Bogar, Krisztian; Kaynak, F. Betuel; Baeckvall, Jan-E.
Journal of the American Chemical Society, 2005 , vol. 127, # 24 p. 8817 - 8825
反应条件
Rhodococcus erythropolis DSM 43066 cells; alcohol dehydrogenase from Lactobacillus kefir; glucose dehydrogenase BS; D-glucose; nicotinamide adenine dinucleotide in alkaline aq. solution T=30°C; pH=7.5; 16 h; Title compound not separated from byproducts.;
参考文献
Voss, Constance V.; Gruber, Christian C.; Kroutil, Wolfgang
Angewandte Chemie - International Edition, 2008 , vol. 47, # 4 p. 741 - 745
反应条件
CAL-B in di-isopropyl ether T=30°C; Esterification; 5 h; Enzymatic reaction;
参考文献
Kita, Yasuyuki; Takebe, Yasushi; Murata, Kenji; Naka, Tadaatsu; Akai, Shuji
Journal of Organic Chemistry, 2000 , vol. 65, # 1 p. 83 - 88
反应条件
D-glucose; Yarrowia lipolytica YL10; peptone in N,N-dimethyl-formamide T=28°C; Oxidation; 72 h; Microbiological reaction; Title compound not separated from byproducts;
参考文献
Fantin, Giancarlo; Fogagnolo, Marco; Medici, Alessandro; Pedrini, Paola; Fontana, Silvia
Tetrahedron Asymmetry, 2000 , vol. 11, # 11 p. 2367 - 2373
反应条件
In(OSO2CF3)3 in dichloromethane T=20°C; 4 h;
参考文献
Chen, Shui-Ling; Hu, Qi-Ying; Loh, Teck-Peng
Organic Letters, 2004 , vol. 6, # 19 p. 3365 - 3367
反应条件
Tris-HCl buffer T=30°C; pH=7.5; 24 h; Enzymatic reaction; enantioselective reaction;
参考文献
Bisogno, Fabricio R.; Lavandera, Ivan; Kroutil, Wolfgang; Gotor, Vicente
Journal of Organic Chemistry, 2009 , vol. 74, # 4 p. 1730 - 1732
反应条件
whole cells of Rhodococcus ruber DSM 44541; acetone in phosphate buffer T=24°C; Oppenauer oxidation; pH=8.0;
参考文献
Stampfer, Wolfgang; Kosjek, Birgit; Faber, Kurt; Kroutil, Wolfgang
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 402 - 406
反应条件
Lipase PS; tert-butyl methyl ether T=30°C; Esterification; 20 h; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Kita, Yasuyuki; Takebe, Yasushi; Murata, Kenji; Naka, Tadaatsu; Akai, Shuji
Journal of Organic Chemistry, 2000 , vol. 65, # 1 p. 83 - 88
反应条件
Yield given. Yields of byproduct given;
参考文献
Wang, Yi-Fong; Yakovlevsky, Kirill; Zhang, Bailing; Margolin, Alexey L.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3488 - 3495
反应条件
1: 42 percent / PBr3, pyridine / diethyl ether 2: 60 percent / dimethylsulfoxide 3: 67 percent / KOH / ethane-1,2-diol; H2O; ethanol / 18 h / Heating 4: 86 percent / oxalyl chloride, pyridine / benzene / 2 h / Ambient temperature 5: 76 percent / triethyl amine / diethyl ether / 1 h / Ambient temperature 6: 82 percent / diethyl ether / Ambient temperature 7: 17 percent / acetonitrile / Irradiation View Scheme
参考文献
Charlton, James Leslie.; Lai, Hoi Kiong.; Lypka, Gerald Nicholas
Canadian Journal of Chemistry, 1980 , vol. 58, p. 458 - 462
