1-苯基-3-(吡咯烷-1-基)-1-丙醇合成路线 (共 5 条)
反应条件
sodium tetrahydroborate in methanol
参考文献
Sharma. V. L.; Bhandari, Kalpana; Chatterjee, S. K.; Satyanarayana, K. V.; Dua, P. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, # 4 p. 393 - 396
反应条件
1: sodium tetrahydroborate / methanol / 24 h / 20 °C / Inert atmosphere
2: sodium iodide / acetone / 48 h / Inert atmosphere; Reflux
3: tetrahydrofuran / 4 h / Inert atmosphere; Reflux
View Scheme
参考文献
Park, Ju-Young; Kim, Seung-Woo; Lee, Ja-Kyeong; Im, Weon Bin; Jin, Byung Kwan; Yoon, Sung-Hwa
Biological and Pharmaceutical Bulletin, 2011 , vol. 34, # 4 p. 538 - 544
反应条件
in tetrahydrofuran
4 h; Inert atmosphereReflux;
参考文献
Park, Ju-Young; Kim, Seung-Woo; Lee, Ja-Kyeong; Im, Weon Bin; Jin, Byung Kwan; Yoon, Sung-Hwa
Biological and Pharmaceutical Bulletin, 2011 , vol. 34, # 4 p. 538 - 544
反应条件
1: 60 percent / conc. HCl / ethanol / 6 h / Heating
2: 75 percent / NaBH4 / methanol
View Scheme
参考文献
Sharma. V. L.; Bhandari, Kalpana; Chatterjee, S. K.; Satyanarayana, K. V.; Dua, P. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, # 4 p. 393 - 396
反应条件
1: sodium iodide / acetone / 48 h / Inert atmosphere; Reflux
2: tetrahydrofuran / 4 h / Inert atmosphere; Reflux
View Scheme
参考文献
Park, Ju-Young; Kim, Seung-Woo; Lee, Ja-Kyeong; Im, Weon Bin; Jin, Byung Kwan; Yoon, Sung-Hwa
Biological and Pharmaceutical Bulletin, 2011 , vol. 34, # 4 p. 538 - 544