N-Cbz-L-天冬氨酸 1-甲酯合成路线 （共 25 条）
反应条件
ruthenium trichloride; sodium periodate in tetrachloromethane; water; acetonitrile 60 h;
参考文献
Ranganathan, Subramania; Ranganathan, Darshan; Bhattacharyya, Dipti
Journal of the Chemical Society, Chemical Communications, 1987 , # 14 p. 1085 - 1086
反应条件
1: SOCl2 2: tBuONO View Scheme
参考文献
Ottersbach, Philipp A.; Schmitz, Janina; Schnakenburg, Gregor; Guetschow, Michael
Organic Letters, 2013 , vol. 15, # 3 p. 448 - 451
反应条件
triethylamine in dichloromethane T=0°C; 2 h; add of cat.: DMAP, 1 h; Title compound not separated from byproducts;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
1: NaHCO3 / toluene; H2O 2: SOCl2 3: tBuONO View Scheme
参考文献
Wuensch,E.; Zwick,A.
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1963 , vol. 333, p. 108 - 113
反应条件
1.1: acetic anhydride / 16 h 2.1: ethyl acetate / 5 h / 20 °C 2.3: pH 2 View Scheme
参考文献
Chandan, Nandkishkor; Moloney, Mark G.
Tetrahedron Letters, 2013 , vol. 54, # 15 p. 1987 - 1990
反应条件
1: N-methyl morpholine / ethyl acetate / 0.25 h 2: ethyl acetate; diethyl ether / 4 h / 0 °C 3: silver benzoate, Et3N / methanol 4: 94 percent / 50percent CF3COOH / CH2Cl2 / Ambient temperature View Scheme
参考文献
Misiti; Santaniello; Zappia
Synthetic Communications, 1992 , vol. 22, # 6 p. 883 - 891
反应条件
1: ethyl acetate; diethyl ether / 4 h / 0 °C 2: silver benzoate, Et3N / methanol 3: 94 percent / 50percent CF3COOH / CH2Cl2 / Ambient temperature View Scheme
参考文献
Misiti; Santaniello; Zappia
Synthetic Communications, 1992 , vol. 22, # 6 p. 883 - 891
反应条件
N,N-dicyclohexylamine in diethyl ether
参考文献
Scoffone,E. et al.
Gazzetta Chimica Italiana, 1964 , vol. 94, p. 695 - 709
反应条件
1: H2SO4 / CH2Cl2 2: dicyclohexylamine View Scheme
参考文献
Scoffone,E. et al.
Gazzetta Chimica Italiana, 1964 , vol. 94, p. 695 - 709
反应条件
trifluoroacetic acid
参考文献
Munekata,E. et al.
Bulletin of the Chemical Society of Japan, 1973 , vol. 46, p. 3187 - 3193
