1-(1-甲基乙基)-1H-苯并三唑-6-羧酸合成路线

参考文献

Pfizer Inc.
Patent: US2003/78432 A1, 2003 ;

参考文献

McClure, Kim F.; Abramov, Yuriy A.; Laird, Ellen R.; Barberia, John T.; Cai, Weiling; Carty, Thomas J.; Cortina, Santo R.; Danley, Dennis E.; Dipesa, Alan J.; Donahue, Kathleen M.; Dombroski, Mark A.; Elliott, Nancy C.; Gabel, Christopher A.; Han, Seungil; Hynes, Thomas R.; LeMotte, Peter K.; Mansour, Mahmoud N.; Marr, Eric S.; Letavic, Michael A.; Pandit, Jayvardhan; Ripin, David B.; Sweeney, Francis J.; Tan, Douglas; Tao, Yong
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5728 - 5737

619-05-63,4-二氨基苯甲酸

467235-05-81-(1-甲基乙基)-1H-苯并三唑-6-羧酸

参考文献

McClure, Kim F.; Abramov, Yuriy A.; Laird, Ellen R.; Barberia, John T.; Cai, Weiling; Carty, Thomas J.; Cortina, Santo R.; Danley, Dennis E.; Dipesa, Alan J.; Donahue, Kathleen M.; Dombroski, Mark A.; Elliott, Nancy C.; Gabel, Christopher A.; Han, Seungil; Hynes, Thomas R.; LeMotte, Peter K.; Mansour, Mahmoud N.; Marr, Eric S.; Letavic, Michael A.; Pandit, Jayvardhan; Ripin, David B.; Sweeney, Francis J.; Tan, Douglas; Tao, Yong
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5728 - 5737

467235-05-81-(1-甲基乙基)-1H-苯并三唑-6-羧酸+

79-37-8草酰氯

467235-06-91-异丙基-N-甲氧基-N-甲基-1H-苯并[d][1,2,3]噻唑-6-羧酰胺

参考文献

Pfizer Inc.
Patent: US2003/78432 A1, 2003 ;

467235-05-81-(1-甲基乙基)-1H-苯并三唑-6-羧酸

467235-06-91-异丙基-N-甲氧基-N-甲基-1H-苯并[d][1,2,3]噻唑-6-羧酰胺

参考文献

McClure, Kim F.; Abramov, Yuriy A.; Laird, Ellen R.; Barberia, John T.; Cai, Weiling; Carty, Thomas J.; Cortina, Santo R.; Danley, Dennis E.; Dipesa, Alan J.; Donahue, Kathleen M.; Dombroski, Mark A.; Elliott, Nancy C.; Gabel, Christopher A.; Han, Seungil; Hynes, Thomas R.; LeMotte, Peter K.; Mansour, Mahmoud N.; Marr, Eric S.; Letavic, Michael A.; Pandit, Jayvardhan; Ripin, David B.; Sweeney, Francis J.; Tan, Douglas; Tao, Yong
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5728 - 5737

467235-05-81-(1-甲基乙基)-1H-苯并三唑-6-羧酸+

6638-79-5二甲羟胺盐酸盐

467235-06-91-异丙基-N-甲氧基-N-甲基-1H-苯并[d][1,2,3]噻唑-6-羧酰胺

参考文献

Pfizer Products Inc.
Patent: EP1247810 A1, 2002 ;
Location in patent: Page 59 ;

467235-05-81-(1-甲基乙基)-1H-苯并三唑-6-羧酸

467235-07-01-异丙基-1H-苯并[d][1,2,3]噻唑-5-甲醛

参考文献

McClure, Kim F.; Abramov, Yuriy A.; Laird, Ellen R.; Barberia, John T.; Cai, Weiling; Carty, Thomas J.; Cortina, Santo R.; Danley, Dennis E.; Dipesa, Alan J.; Donahue, Kathleen M.; Dombroski, Mark A.; Elliott, Nancy C.; Gabel, Christopher A.; Han, Seungil; Hynes, Thomas R.; LeMotte, Peter K.; Mansour, Mahmoud N.; Marr, Eric S.; Letavic, Michael A.; Pandit, Jayvardhan; Ripin, David B.; Sweeney, Francis J.; Tan, Douglas; Tao, Yong
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5728 - 5737