2,3-二甲基-3-苄基-3H-吲哚合成路线 （共 8 条）
反应条件
(η3-allyl)2Pd(cod)BF4; triethyl borane; potassium phenolate; bis[2-(diphenylphosphino)phenyl] ether in toluene
T=75°C; 5 h; Inert atmosphere;
参考文献
Montgomery, Thomas D.; Zhu, Ye; Kagawa, Natsuko; Rawal, Viresh H.
Organic Letters, 2013 , vol. 15, # 5 p. 1140 - 1143
反应条件
1: 2,3-dimethyl-indole With potassium tert-butylate in 1,4-dioxane
T=20°C; 0.5 h; Inert atmosphere;
2: With triethyl borane in 1,4-dioxane; hexane
0.5 h; Inert atmosphere;
3: benzyl bromide in 1,4-dioxane; hexane
T=20°C; 12 h; Inert atmosphere;
参考文献
Lin, Aijun; Yang, Jiong; Hashim, Mohamed
Organic Letters, 2013 , vol. 15, # 8 p. 1950 - 1953
反应条件
1: 2,3-dimethyl-indole With (η3-allyl)2Pd(cod)BF4; bis[2-(diphenylphosphino)phenyl] ether in toluene
T=20°C; 0.0833333 h; Inert atmosphere;
2: PhCH2OCO2Me With N,O-bis-(trimethylsilyl)-acetamide; triethyl borane in hexane; toluene
T=50°C; 18 h; Inert atmosphere;
参考文献
Zhu, Ye; Rawal, Viresh H.
Journal of the American Chemical Society, 2012 , vol. 134, # 1 p. 111 - 114
反应条件
perchloric acid in ethanol
Fischer indolization; Heating;
参考文献
Zimmermann, Thomas; Hennig, Lothar
Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 2 p. 263 - 269
反应条件
EtMgI; diethyl ether
Behandeln der Reaktionsloesung mit Benzylchlorid.;
参考文献
Nakasaki et al.
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1262,1264
Chem.Abstr., 1957 , p. 17878
反应条件
(η3-allyl)2Pd(cod)BF4; potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether in tert-butyl alcohol
T=80°C; 4.5 h; Inert atmosphere;
参考文献
Zhu, Ye; Rawal, Viresh H.
Journal of the American Chemical Society, 2012 , vol. 134, # 1 p. 111 - 114
反应条件
diethyl ether; ammonia; sodium amide
Anschliessendes Behandeln mit Benzylchlorid;
参考文献
Nakazaki
Bulletin of the Chemical Society of Japan, 1959 , vol. 32, p. 838
参考文献
Garry
Annales de Chimie (Cachan, France), 1942 , vol. <11>17, p. 5,15
