3,4-二甲氧基苯甲酰乙酸乙酯合成路线 (共 32 条)
反应条件
1: 67 percent / aq. KOH / 40 h / Ambient temperature 2: conc. HCl / 0.5 h / Heating View Scheme
参考文献
Cragg, John E.; Herbert, Richard B.; Jackson, Frederick B.; Moody, Christopher J.; Nicolson, Ian T.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2477 - 2486
反应条件
4.5 h; Mortierella isabelina; Yields of byproduct given;
参考文献
Bardot, Valerie; Besse, Pascale; Gelas-Miahle, Yvonne; Remuson, Roland; Veschambre, Henri
Tetrahedron Asymmetry, 1996 , vol. 7, # 4 p. 1077 - 1088
反应条件
1: hydrogen chloride; ethanol 2: aqueous KOH-solution 3: sodium ethylate; ethanol / anschliessend Behandeln mit Wasser und Natrium-Amalgam und Erhitzen des Reaktionsprodukts unter verminderten Druck auf 120grad View Scheme
参考文献
Appel et al.
Journal of the Chemical Society, 1937 , p. 738,742
参考文献
Pillon
Bulletin de la Societe Chimique de France, 1954 , p. 9,21
参考文献
Pillon
Bulletin de la Societe Chimique de France, 1955 , p. 39,40
参考文献
Pillon
Bulletin de la Societe Chimique de France, 1954 , p. 9,21
反应条件
sodium hydroxide
24 h;
参考文献
Langenskioeld, Tord; Lounasmaa, Mauri
Heterocycles, 1983 , vol. 20, # 4 p. 671 - 675
反应条件
potassium hydroxide
75 h; Ambient temperature;
参考文献
Irvine, Robert W.; Summers, John C.; Taylor, Walter C.
Australian Journal of Chemistry, 1983 , vol. 36, # 7 p. 1419 - 1430
反应条件
1: 71 percent / 30percent aq.KOH / 75 h / Ambient temperature
2: 88 percent / methanol; diethyl ether / 0 °C
View Scheme
参考文献
Irvine, Robert W.; Summers, John C.; Taylor, Walter C.
Australian Journal of Chemistry, 1983 , vol. 36, # 7 p. 1419 - 1430
反应条件
0.0583333 h; microwave irradiation;
参考文献
Seijas, Julio A.; Vazquez-Tato, M. Pilar; Carballido-Reboredo, Raquel
Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2855 - 2858