5,5-二甲基-2-环己烯-1-酮合成路线 （共 67 条）
反应条件
1: NEt3 / H2O; ethanol 2: NaBH4, CeCl3 / methanol View Scheme
参考文献
Kido, Fusao; Kawada, Yasuhiko; Kato, Michiharu; Yoshikoshi, Akira
Tetrahedron Letters, 1991 , vol. 32, # 43 p. 6159 - 6162
参考文献
Crossley; Renouf
Journal of the Chemical Society, 1907 , vol. 91, p. 74
反应条件
hydrogenchloride; amalgamated zinc
参考文献
Davis,B.R.; Woodgate,P.D.
Journal of the Chemical Society, 1965 , p. 5943 - 5948
参考文献
Auterinen
Suomen Kemistilehti B, 1937 , vol. 10, p. 22
反应条件
sodium hydroxide; dihydrogen peroxide in methanol T=15 - 36°C; 0.166667 h;
参考文献
Bergman, Rolf; Magnusson, Goeran
Journal of Organic Chemistry, 1986 , vol. 51, # 2 p. 212 - 217
反应条件
potassium iodide; zinc in methanol
1 h; Heating / reflux;
参考文献
SERENEX, INC.
Patent: US2008/119457 A1, 2008 ;
Location in patent: Page/Page column 50 ;
反应条件
1: With diisobutylaluminium hydride in diethyl ether
0.5 h;
2: With water; ammonium chloride in diethyl ether
1 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/88716 A1, 2006 ;
Location in patent: Page/Page column 47-48 ;
WO 2006/088716 A1
反应条件
lithium aluminium tetrahydride in diethyl ether
1 h; Ambient temperature;
参考文献
Winska, Katarzyna; Grudniewska, Aleksandra; Chojnacka, Anna; Bialonska, Agata; Wawrzenczyk, Czeslaw
Tetrahedron Asymmetry, 2010 , vol. 21, # 6 p. 670 - 678
反应条件
1: With ammonium cerium(IV) nitrate in methanol
T=20°C; 16 h;
2: With lithium aluminium tetrahydride in diethyl ether
T=0 - 20°C; 1 h;
3: With silica gel in dichloromethane
3 h; Further stages.;
参考文献
Donaldson, Lauren R.; Haigh, David; Hulme, Alison N.
Tetrahedron, 2008 , vol. 64, # 19 p. 4468 - 4477
反应条件
mercury dichloride in water; acetonitrile
T=50 - 80°C;
参考文献
Mimura, Tetsuya; Nakai, Takeshi
Chemistry Letters, 1980 , p. 1099 - 1102
