6-硝基苯并恶唑-2(3H)-酮合成路线 （共 20 条）
参考文献
Lespagnol,A. et al.
Chimica Therapeutica, 1967 , vol. 2, p. 343 - 346
反应条件
(i) NaOEt, EtOH, (ii) /BRN= 98439/, xylene; Multistep reaction;
参考文献
Advani,S.B.; Sam,J.
Journal of Heterocyclic Chemistry, 1968 , vol. 5, p. 119 - 122
反应条件
2: palladium/charcoal; ethanol / Hydrogenation View Scheme
参考文献
Abdelaal; Kong; Bauer
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1069 - 1076
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 42, p. 443
Chemische Berichte, , vol. 20, p. 179
参考文献
Clark; Pessolano
Journal of the American Chemical Society, 1958 , vol. 80, p. 1662
反应条件
1: <PhCH2NMe3>OH 2: aq. HCl View Scheme
参考文献
Lespagnol,A. et al.
Chimica Therapeutica, 1967 , vol. 2, p. 343 - 346
反应条件
hydrogen; palladium 10 on activated carbon in tetrahydrofuran; water T=20°C; 9 h;
参考文献
SHIONOGI and CO., LTD.
Patent: EP1988077 A1, 2008 ;
Location in patent: Page/Page column 68 ;
反应条件
1: (i) aq. KOH, EtOH, (ii) /BRN= 124500/
2: aq. KOH / ethanol / Heating
3: dimethylformamide / Heating
View Scheme
参考文献
Savitskaya,N.V. et al.
Pharmaceutical Chemistry Journal, 1976 , vol. 10, # 8 p. 1051 - 1056
Khimiko-Farmatsevticheskii Zhurnal, 1976 , vol. 10, # 8 p. 66 - 72
反应条件
(i) NaOEt, EtOH, (ii) aq. KOH, (iii) /BRN= 124500/; Multistep reaction;
参考文献
Savitskaya,N.V. et al.
Pharmaceutical Chemistry Journal, 1976 , vol. 10, # 8 p. 1051 - 1056
Khimiko-Farmatsevticheskii Zhurnal, 1976 , vol. 10, # 8 p. 66 - 72
参考文献
v. Chelmicki
Journal fuer Praktische Chemie (Leipzig), 1890 , vol. <2> 42, p. 443
Chemische Berichte, 1887 , vol. 20, p. 179
