N-[2-(3,4-二羟基苯基)乙基]-2-甲基丙烯酰胺合成路线 （共 3 条）
反应条件
1: 2-(3,4-dihydroxyphenyl)ethylamine hydrochloride With Na2B4O7; sodium hydrogencarbonate in water
Inert atmosphere;
2: methacrylic anhydride With sodium hydroxide in tetrahydrofuran; water
T=20°C; pH=8-9; 17 h;
参考文献
White, Evan M.; Seppala, Jonathan E.; Rushworth, Parker M.; Ritchie, Branson W.; Sharma, Suraj; Locklin, Jason
Macromolecules, 2013 , vol. 46, # 22 p. 8882 - 8887
反应条件
1: 2-(3,4-dihydroxyphenyl)ethylamine hydrochloride With Na2B4O7; sodium carbonate in water
pH=> 9.5; Inert atmosphere;
2: 2-methyl-acryloyl chloride With sodium carbonate in water
T=20°C; pH=Ca. 9.8; Inert atmosphereCooling with ice;
3: With hydrogenchloride in water
pH=1 - 2;
参考文献
Ham, Hyun Ok; Liu, Zhongqiang; Lau, K. H. Aaron; Lee, Haeshin; Messersmith, Phillip B.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 3 p. 732 - 736
反应条件
Na2CO3*10H2O; sodium hydrogencarbonate in tetrahydrofuran; water
T=20°C; 8 h; Inert atmosphere;
参考文献
Niu, Rui; Qiao, Jing; Yu, Hang; Nie, Jun; Yang, Dongzhi
Frontiers of Chemistry in China, 2011 , vol. 6, # 3 p. 221 - 226
