2,6,6-三甲基环己烯-1-甲醇合成路线 （共 39 条）
反应条件
aluminium phenoxide; acetone
参考文献
Yamashita; Honjo
Nippon Kagaku Kaishi, 1942 , vol. 63, p. 1335
Chem.Abstr., 1947 , p. 3041
反应条件
Al tri-t-BuO-; acetone
参考文献
Yamashita; Honjo
Nippon Kagaku Kaishi, 1942 , vol. 63, p. 1335
Chem.Abstr., 1947 , p. 3041
反应条件
aluminium phenoxide; acetone
参考文献
Yamashita; Honjo
Nippon Kagaku Kaishi, 1942 , vol. 63, p. 1335
Chem.Abstr., 1947 , p. 3041
反应条件
Al tri-t-BuO-; acetone
参考文献
Yamashita; Honjo
Nippon Kagaku Kaishi, 1942 , vol. 63, p. 1335
Chem.Abstr., 1947 , p. 3041
反应条件
1: Zn-Cu couple, I2 / diethyl ether / 2 h / Heating
2: 74 percent / pyridine, CrO3 / CH2Cl2 / 1 h / Ambient temperature
3: 77 percent / n-BuLi / tetrahydrofuran; hexane / a) RT, 22 h, b) 0 deg C, 60 h
4: 93 percent / DIBAL / diethyl ether; hexane / 1 h / Ambient temperature
5: 4.7 g / MnO2 / hexane; CH2Cl2 / 16 h / Ambient temperature
6: 94 percent / diethyl ether; tetrahydrofuran / 0.5 h / 20 °C
7: 72 percent / MnO2 / hexane; CH2Cl2 / 16 h / Ambient temperature
View Scheme
参考文献
Dawson; Hobbs; Chan; Chao
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1214 - 1223
反应条件
4-(N,N-dimethlyamino)pyridine in pyridine
72 h; Ambient temperature; Yield given;
参考文献
Uzarewicz; Dresler
Polish Journal of Chemistry, 1998 , vol. 72, # 8 p. 1921 - 1930
反应条件
titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2R,3R)-tartrate in dichloromethane
T=-20°C; Sharpless asymmetric epoxidation; 12 h;
参考文献
Vaz, Belen; Alvarez, Rosana; Souto, Jose A.; De Lera, Angel R.
Synlett, 2005 , # 2 art. no. G39104ST, p. 294 - 298
反应条件
(+)-Weinsaeure-diethylester
Katsuki-Sharpless asymmetric epoxidation; Title compound not separated from byproducts;
参考文献
Srikrishna, Adusumilli; Nagamani, Shankarnarayan A.; Jagadeesh, Setti G.
Tetrahedron Asymmetry, 2005 , vol. 16, # 9 p. 1569 - 1571
反应条件
lead(IV) acetate; oxygen; ozone in dichloromethane
T=0°C; 1.25 h;
参考文献
Alvarez-Manzaneda; Chahboun; Cano; Cabrera Torres; Alvarez; Haidour; Ramos Lopez
Tetrahedron Letters, 2006 , vol. 47, # 37 p. 6619 - 6622
反应条件
1: PBr3
2: dimethylsulfoxide
3: aq. KOH
View Scheme
参考文献
Bhar, Shanta S.; Ramana
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8935 - 8937
