2,6,6-三甲基环己烯-1-甲醇合成路线 （共 39 条）
反应条件
1: PBr3 / diethyl ether
2: dimethylformamide
View Scheme
参考文献
Akita, Hiroyuki; Tanis, Steven P.; Adams, Michael; Balogh-Nair, Valeria; Nakanishi, Koji
Journal of the American Chemical Society, 1980 , vol. 102, # 20 p. 6370 - 6372
反应条件
1: PBr3
2: dimethylsulfoxide
View Scheme
参考文献
Bhar, Shanta S.; Ramana
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8935 - 8937
反应条件
phosphorus tribromide in diethyl ether; hexane
T=-30 - 20°C; 15 h;
参考文献
Crombie, Barry S.; Smith, Colin; Varnavas, Christalla Z.; Wallace, Timothy W.
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 2 p. 206 - 215
反应条件
1: propionic acid / toluene / 168 h / 180 °C
2: 10percent aq.NaOH / methanol / 8 h / Heating
3: (COCl)2 / benzene / 5 h / Ambient temperature
4: diethyl ether; diethyl ether / 3 h / Ambient temperature
View Scheme
参考文献
Srikrishna, A.; Krishnan, K.
Tetrahedron Letters, 1989 , vol. 30, # 47 p. 6577 - 6580
反应条件
1: K2CO3 / benzene / Heating
2: LiAlH4 / diethyl ether / Heating
View Scheme
参考文献
Ehrenfreund,J. et al.
Helvetica Chimica Acta, 1974 , vol. 57, p. 1098 - 1116
反应条件
in methanol
T=20°C; 18 h;
参考文献
ACUCELA INC.
Patent: WO2008/131368 A2, 2008 ;
Location in patent: Page/Page column 134; 136 ;
反应条件
1: PBr3 / diethyl ether; pentane / 1.) -30 deg C, 2 h, 2.) room temperature, overnight
2: 22 percent / ethyl acetate / 1 h / Heating
View Scheme
参考文献
Andrewes, Arthur G.; Borch, Gunner; Liaaen-Jensen, Synnoeve
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1984 , vol. 38, # 10 p. 871 - 876
反应条件
cerium(III) chloride; isopropyl alcohol
6 h; Heating;
参考文献
Uzarewicz; Dresler
Polish Journal of Chemistry, 1998 , vol. 72, # 8 p. 1921 - 1930
反应条件
cerium(III) chloride; tert-butyl alcohol
6 h; Heating;
参考文献
Uzarewicz; Dresler; Scianowski
Polish Journal of Chemistry, 1998 , vol. 72, # 4 p. 710 - 718
反应条件
cerium(III) chloride
4 h; Heating;
参考文献
Uzarewicz; Dresler; Scianowski
Polish Journal of Chemistry, 1998 , vol. 72, # 4 p. 710 - 718
Title/Abstract Full Text View citing articles Show Details
Uzarewicz; Dresler
Polish Journal of Chemistry, 1998 , vol. 72, # 8 p. 1921 - 1930
