苯并[1,3]二氧杂环戊烯-5-基甲基-苄基-胺合成路线 （共 11 条）
反应条件
ethanol; platinum
Hydrogenation;
参考文献
Adorni; Ishii
Anales de la Asociacion Quimica Argentina (1921-2001), 1945 , vol. 33, p. 71,75
反应条件
1: With hydrogenchloride in diethyl ether
T=23°C; 1 h; Inert atmosphere;
2: With sodium hydrogencarbonate in methanol; water
T=23°C; 2 h; Inert atmosphere;
参考文献
Cheng, Chen; Brookhart, Maurice
Journal of the American Chemical Society, 2012 , vol. 134, # 28 p. 11304 - 11307
反应条件
1: Na2SO4 / CH2Cl2 / 2 h
2: 2.13 g / NaBH4 / methanol / 1 h / 20 °C
View Scheme
参考文献
Orito, Kazuhiko; Horibata, Akiyoshi; Nakamura, Takatoshi; Ushito, Harumi; Nagasaki, Hideo; Yuguchi, Motoki; Yamashita, Satoshi; Tokuda, Masao
Journal of the American Chemical Society, 2004 , vol. 126, # 44 p. 14342 - 14343
反应条件
1: Na2SO4 / CH2Cl2 / 2 h
2: 2.13 g / NaBH4 / methanol / 1 h / 20 °C
View Scheme
参考文献
Orito, Kazuhiko; Horibata, Akiyoshi; Nakamura, Takatoshi; Ushito, Harumi; Nagasaki, Hideo; Yuguchi, Motoki; Yamashita, Satoshi; Tokuda, Masao
Journal of the American Chemical Society, 2004 , vol. 126, # 44 p. 14342 - 14343
反应条件
ruthenium(III) chloride*(x)H2O; potassium carbonate; triphenylphosphine
T=140°C; 9 h; Inert atmosphere;
参考文献
Cui, Xinjiang; Zhang, Yan; Shi, Feng; Deng, Youquan
Chemistry - A European Journal, 2011 , vol. 17, # 9 p. 2587 - 2591
反应条件
1.1: 83 percent / DEAD; Ph3P / tetrahydrofuran
2.1: NaBH4 / propan-2-ol; toluene; H2O
3.1: p-TsOH / CH2Cl2
4.1: t-BuOK / tetrahydrofuran
4.2: tetrahydrofuran
5.1: TFA / tetrahydrofuran; H2O
5.2: NaOH / diethyl ether
View Scheme
参考文献
Glatz, Heiko; Bannwarth, Willi
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 149 - 152
反应条件
1.1: NaBH4 / propan-2-ol; toluene; H2O
2.1: p-TsOH / CH2Cl2
3.1: t-BuOK / tetrahydrofuran
3.2: tetrahydrofuran
4.1: TFA / tetrahydrofuran; H2O
4.2: NaOH / diethyl ether
View Scheme
参考文献
Glatz, Heiko; Bannwarth, Willi
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 149 - 152
反应条件
1.1: p-TsOH / CH2Cl2
2.1: t-BuOK / tetrahydrofuran
2.2: tetrahydrofuran
3.1: TFA / tetrahydrofuran; H2O
3.2: NaOH / diethyl ether
View Scheme
参考文献
Glatz, Heiko; Bannwarth, Willi
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 149 - 152
反应条件
1: TFA / tetrahydrofuran; H2O
2: NaOH / diethyl ether
View Scheme
参考文献
Glatz, Heiko; Bannwarth, Willi
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 149 - 152
反应条件
1: With trifluoroacetic acid in tetrahydrofuran; water
2: With sodium hydroxide in diethyl ether
参考文献
Glatz, Heiko; Bannwarth, Willi
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 149 - 152
