1-甲基-6,7-二甲氧基-3,4-二氢异喹啉合成路线 （共 34 条）
反应条件
hydrogenchloride 18 h; Heating;
参考文献
Orito, Kazuhiko; Matsuzaki, Tsutomu; Suginome, Hiroshi; Rodrigo, Russel
Heterocycles, 1988 , vol. 27, # 10 p. 2403 - 2412
反应条件
1.1: 14.48 g / phosphoryl chloride / toluene / 1 h / Heating 2.1: 59.7 percent / bromophenol blue; conc. hydrochloric acid / methanol / 0 - 20 °C 3.1: KHMDS / tetrahydrofuran / 3 h / -78 °C 3.2: 177.5 mg / aq. NiCl2 / methanol / 20 °C View Scheme
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Statkova-Abeghe, Stela; Angelov, Plamen
Heterocycles, 2006 , vol. 68, # 2 p. 387 - 393
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; potassium iodide in tetrahydrofuran; chloroform T=40°C; 0.0833333 h;
参考文献
Blacker, A. John; Stirling, Matthew J.; Page, Michael I.
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 642 - 648
反应条件
sulfuric acid in methanol Heating; Yield given;
参考文献
Larsen, Robert D.; Reamer, Robert A.; Corley, Edward G.; Davis, Paul; Grabowski, Edward J. J.; et al.
Journal of Organic Chemistry, 1991 , vol. 56, # 21 p. 6034 - 6038
反应条件
1.1: 59.7 percent / bromophenol blue; conc. hydrochloric acid / methanol / 0 - 20 °C 2.1: KHMDS / tetrahydrofuran / 3 h / -78 °C 2.2: 177.5 mg / aq. NiCl2 / methanol / 20 °C View Scheme
参考文献
Werner, Frank; Blank, Nancy; Opatz, Till
European Journal of Organic Chemistry, 2007 , # 23 p. 3911 - 3915
反应条件
polyphophoric acid T=80 - 100°C;
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Statkova-Abeghe, Stela; Angelov, Plamen
Heterocycles, 2006 , vol. 68, # 2 p. 387 - 393
反应条件
1: 80 percent / pTsOH / 1,2-dichloro-ethane / 0.5 h / Heating 2: polyphophoric acid / 80 - 100 °C View Scheme
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Statkova-Abeghe, Stela; Angelov, Plamen
Heterocycles, 2006 , vol. 68, # 2 p. 387 - 393
反应条件
acetic acid; zinc 1 h; Reflux;
参考文献
Ishikawa, Kyoko; Tomatsu, Miyuki; Nagase, Hiroshi; Fujii, Hideaki
Heterocycles, 2014 , vol. 88, # 2 p. 1051 - 1063
反应条件
tin(IV) chloride T=120°C;
参考文献
Lora-Tamayo et al.
Chemistry and Industry (London, United Kingdom), 1959 , p. 657
Chemische Berichte, 1960 , vol. 93, p. 289 Anm. 5
反应条件
potassium hydroxide; ethanol
参考文献
Osbond
Journal of the Chemical Society, 1951 , p. 3464,3469
