1-甲基-6,7-二甲氧基-3,4-二氢异喹啉合成路线 (共 34 条)
反应条件
in ethanol; water addn. of 5percent aq. HCl to the ethanol soln. (cooling, stirring), stirring for 30min, refluxing for 30min;;
参考文献
Yamada, S.-I.; Ikegami, S.
Chem. Pharm. Bull. (Tokyo), 1966 , vol. 14, p. 1382 - 1388
Full Text Show Details
Gmelin Handbook: B: B-Verb.14, 3.14.1, page 144 - 145
参考文献
Kaufmann; Radosevic
Chemische Berichte, 1916 , vol. 49, p. 680,682
参考文献
Spaeth; Polgar
Monatshefte fuer Chemie, 1929 , vol. 51, p. 199
反应条件
1.1: 75 percent / methanol; acetone / 0.5 h / Heating 2.1: NaBH4 / methanol / 2 h 2.2: 97 percent / aq. HCl / methanol View Scheme
参考文献
Cui, Wenhua; Iwasa, Kinuko; Tokuda, Harukuni; Kashihara, Akiko; Mitani, Yosuke; Hasegawa, Tomoko; Nishiyama, Yumi; Moriyasu, Masataka; Nishino, Hoyoku; Hanaoka, Miyoji; Mukai, Chisato; Takeda, Kazuyoshi
Phytochemistry, 2006 , vol. 67, # 1 p. 70 - 79
反应条件
1: 75 percent / phenethole / 10percent Pd/C / 1 h / Heating 2: 25 percent / SeO2 3: 50 percent / NH2OH View Scheme
参考文献
Postaire, E.; Martinez, D.; Viel, C.; Chastagnier, M.; Hamon, M.
Bulletin de la Societe Chimique de France, 1988 , # 6 p. 982 - 988
反应条件
indium; ammonium chloride in ethanol Heating;
参考文献
Iali, Wissam; Paglia, Frederic La; Pfeffer, Michel; Djukic, Jean-Pierre; Goff, Xavier-Frederic Le; Sredojevic, Dusan
Chemical Communications (Cambridge, United Kingdom), 2012 , vol. 48, # 83 p. 10310 - 10312,3
反应条件
hydrogen; Pd-BaSO4 in methanol T=40°C; P=750.06 Torr;
参考文献
Glusa; Gruner; Hagen; Lohmann; Foken
Pharmazie, 1990 , vol. 45, # 6 p. 408 - 410
反应条件
pyridine in ethylene glycol dimethyl ether T=0°C; 0.25 h;
参考文献
Saa, Carlos; Guitian, Enrique; Castedo, Luis; Suau, Rafael; Saa, Jose Manuel
Journal of Organic Chemistry, 1986 , vol. 51, # 14 p. 2781 - 2784
反应条件
in butanone 9 h; Heating;
参考文献
Pitts; Harrison; Moody
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 955 - 977
反应条件
1: 75 percent / phenethole / 10percent Pd/C / 1 h / Heating
2: 25 percent / SeO2
View Scheme
参考文献
Postaire, E.; Martinez, D.; Viel, C.; Chastagnier, M.; Hamon, M.
Bulletin de la Societe Chimique de France, 1988 , # 6 p. 982 - 988