联苯-4,4-草酸二乙酯合成路线 （共 84 条）
反应条件
1: 4-bromo-benzoic acid ethyl ester With N-ethyl-N,N-diisopropylamine; palladium dichloride; biphenyl-2-yl-di-tert-butyl-phosphane in 1-methyl-pyrrolidin-2-one T=60°C; 0.166667 h; 2: 1,2-diethoxy-1,1,2,2-tetramethyldisilane in dichloromethane T=60°C; 10 h;
参考文献
Denmark, Scott E.; Kallemeyn, Jeffrey M.
Organic Letters, 2003 , vol. 5, # 19 p. 3483 - 3486
反应条件
N,N,N',N,-tetramethylethylenediamine; PdCl2(Amphos)2; zinc in water T=20°C; Negishi-like cross-coupling; 72 h; Inert atmosphere;
参考文献
Duplais, Christophe; Krasovskiy, Arkady; Lipshutz, Bruce H.
Organometallics, 2011 , vol. 30, # 22 p. 6090 - 6097
反应条件
chromium dichloride; manganese; nickel dichloride in ethylene glycol dimethyl ether; N,N-dimethyl-formamide 5 h; Ambient temperature; Yields of byproduct given;
参考文献
Fuerstner, Alois; Shi, Nongyuan
Journal of the American Chemical Society, 1996 , vol. 118, # 49 p. 12349 - 12357
反应条件
palladium diacetate in N,N-dimethyl-formamide T=50°C; Negishi coupling; 16 h; Title compound not separated from byproducts;
参考文献
Alimardanov, Asaf; Schmieder-Van De Vondervoort, Lizette; De Vries, Andre H. M.; De Vries, Johannes G.
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1812 - 1817
反应条件
palladium diacetate in N,N-dimethyl-formamide T=50°C; Negishi coupling; 16 h; Title compound not separated from byproducts;
参考文献
Alimardanov, Asaf; Schmieder-Van De Vondervoort, Lizette; De Vries, Andre H. M.; De Vries, Johannes G.
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1812 - 1817
反应条件
triethylamine; palladium diacetate T=100°C; Heck reaction; 24 h;
参考文献
Bernini, Roberta; Cacchi, Sandro; De Salve, Ilse; Fabrizi, Giancarlo
Synlett, 2006 , # 18 p. 2947 - 2952
反应条件
1: Et3N / Herrmann catalyst / acetonitrile / 100 °C 2: 30 percent / Et3N / Pd(OAc)2 / 24 h / 100 °C View Scheme
参考文献
Bernini, Roberta; Cacchi, Sandro; De Salve, Ilse; Fabrizi, Giancarlo
Synlett, 2006 , # 18 p. 2947 - 2952
反应条件
1: Et3N / Herrmann catalyst / acetonitrile / 100 °C 2: 5 percent / Et3N / Pd(OAc)2 / 24 h / 100 °C View Scheme
参考文献
Bernini, Roberta; Cacchi, Sandro; De Salve, Ilse; Fabrizi, Giancarlo
Synlett, 2006 , # 18 p. 2947 - 2952
反应条件
1: Et3N / Herrmann catalyst / acetonitrile / 100 °C 2: 20 percent / Et3N / Pd(OAc)2 / 24 h / 100 °C View Scheme
参考文献
Bernini, Roberta; Cacchi, Sandro; De Salve, Ilse; Fabrizi, Giancarlo
Synlett, 2006 , # 18 p. 2947 - 2952
反应条件
1: Et3N / Herrmann catalyst / acetonitrile / 100 °C 2: Et3N / Pd(OAc)2 / 24 h / 100 °C View Scheme
参考文献
Bernini, Roberta; Cacchi, Sandro; De Salve, Ilse; Fabrizi, Giancarlo
Synlett, 2006 , # 18 p. 2947 - 2952
