联苯-4,4-草酸二乙酯合成路线 （共 84 条）
反应条件
1: With chloro-trimethyl-silane; ethylene dibromide; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; lithium chloride; cobalt(II) chloride; zinc in tetrahydrofuran T=20°C; 5 h; Inert atmosphere; 2: With iodine in tetrahydrofuran 0.5 h;
参考文献
Jin, Meng-Yi; Yoshikai, Naohiko
Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 1972 - 1978
反应条件
chromium dichloride; manganese; chloro-trimethyl-silane; tetrabutyl ammonium fluoride; nickel dichloride 1.) DMF, DME, 50 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Fuerstner, Alois; Shi, Nongyuan
Journal of the American Chemical Society, 1996 , vol. 118, # 10 p. 2533 - 2534
反应条件
pyridine; tetra-n-butylammonium tetrafluoroborate in acetonitrile T=20°C; Electrolysisiron rod as anode; stainless steel grid as cathode;
参考文献
Gomes, Paulo; Fillon, Hyacinthe; Gosmini, Corinne; Labbe, Eric; Perichon, Jacques
Tetrahedron, 2002 , vol. 58, # 42 p. 8417 - 8424
反应条件
[2,2']bipyridinyl; manganese; cobalt(II) dibromide in acetonitrile T=50°C;
参考文献
Moncomble, Aurelien; Floch, Pascal Le; Lledos, Agusti; Gosmini, Corinne
Journal of Organic Chemistry, 2012 , vol. 77, # 11 p. 5056 - 5062
反应条件
1: 4-iodobenzoic acid ethyl ester; iso-propylmagnesium bromide in tetrahydrofuran T=0°C; 0.333333 h; Inert atmosphere; 2: bis(1,3-benzothiazol-2-yl)methanone in tetrahydrofuran T=0°C; 1 h; Inert atmosphere; 3: With (NH4)2SO4 in tetrahydrofuran; water Inert atmosphere; regioselective reaction;
参考文献
Boga, Carla; Micheletti, Gabriele
European Journal of Organic Chemistry, 2010 , # 29 p. 5659 - 5665
参考文献
Ressia, Jorge A.; Quinzani, Lidia M.; Valles, Enrique M.; Bello, Pablo; Bello, Antonio
Molecular Crystals and Liquid Crystals, 2004 , vol. 420, p. 9 - 33
反应条件
copper(l) iodide; sodium azide; N-methyl-2-(methylamino)ethylamine in dimethyl sulfoxide T=100°C; Inert atmosphere;
参考文献
Markiewicz, John T.; Wiest, Olaf; Helquist, Paul
Journal of Organic Chemistry, 2010 , vol. 75, # 14 p. 4887 - 4890
反应条件
1: sulfuric acid / 4 h / Reflux 2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere 3: potassium phosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 20 - 100 °C / Inert atmosphere View Scheme
参考文献
Gurung, Santosh K.; Kim, Soo Bae; Park, Haeil
Archives of Pharmacal Research, 2010 , vol. 33, # 12 p. 1919 - 1926
反应条件
1: thionyl chloride / pyridine / 10 h / 60 °C 2: EtONa / 20 °C View Scheme
参考文献
Ressia, Jorge A.; Quinzani, Lidia M.; Valles, Enrique M.; Bello, Pablo; Bello, Antonio
Molecular Crystals and Liquid Crystals, 2004 , vol. 420, p. 9 - 33
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate T=20 - 100°C; Suzuki-Miyaura reaction; Inert atmosphere;
参考文献
Gurung, Santosh K.; Kim, Soo Bae; Park, Haeil
Archives of Pharmacal Research, 2010 , vol. 33, # 12 p. 1919 - 1926
