3,5-二羟基苯基乙酸甲酯合成路线 （共 23 条）
反应条件
1: BF3-Et2O
2: NaOMe / methanol
View Scheme
参考文献
Vagstad, Anna L.; Hill, Eric A.; Labonte, Jason W.; Townsend, Craig A.
Chemistry and Biology, 2012 , vol. 19, # 12 p. 1525 - 1534
反应条件
1.1: potassium carbonate; potassium iodide / acetone / 16 h / |Reflux
2.1: sodium hydroxide / water / 16 h / |Reflux
2.2: |Cooling with ice
3.1: oxalyl dichloride; N,N-dimethyl-formamide / toluene / 1 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Resch, Verena; Lechner, Horst; Schrittwieser, Joerg H.; Wallner, Silvia; Gruber, Karl; MacHeroux, Peter; Kroutil, Wolfgang
Chemistry - A European Journal, 2012 , vol. 18, # 41 p. 13173 - 13179
反应条件
1: BF3-Et2O
2: NaOMe / methanol
3: O2, OH-
View Scheme
参考文献
Baker,P.M.; Bycroft,B.W.
Chemical Communications (London), 1968 , p. 71 - 72
